1,372 search results for “chemical space” in the Public website
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Control of Western flower thrips through jasmonate-triggered plant immunity
We showed that constitutive and inducible chemical and morphological defenses against Western flower thrips differ between tomato and chrysanthemum plants.
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The astrochemical factory: A solid base for interstellar reactions
In this thesis chemical and physical processes in the ice mantles on interstellar dust grains are studied.
- Prof Dr Nicole van Dam
- Dr Heiko Vogel
- Prof Dr André Kessler
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Research profiles
The Leiden Institute of Chemistry has opened 5 - 6 staff positions for research related to its two focus areas, Energy & Sustainability and Chemical Biology. We offer an attractive research and teaching environment, including scientific independence, a collaborative atmosphere, attractive start-up packages…
- Prof Dr Caroline Müller
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Molecular Physiology
Molecular Physiology is a research group at the Leiden Institute of Chemistry dedicated to the design, synthesis and application of chemical tools to study important biological and biomedical questions. The group is headed by Prof. Dr. Mario van der Stelt and includes the research lines of Assistant…
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Chemical Biology Lecture: Multicomponent Syntheses of Heterocycles
Lecture
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New generation of graphene biosensors based on smooth surfaces and sharp edges
The surface and the edges of graphene are expected to provide higher sensitivity and specificity in detecting and characterizing single molecules. However fundamental physical limits exist in reaching an ultimate precision in detecting the dynamics of chemical and biological systems. The research in…
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Astronomers spot benzene in planet-forming disk around star for first time
An international team of astronomers including Leiden professor Ewine van Dishoeck has observed the benzene molecule (C6H6) in a planet-forming disk around a young star for the first time. The observations tell us more about the forming of planets in this disc, like our own Earth. The scientists publish…
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Chemical genetic approaches for target validation
PhD defence
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Chemical Similarity: Structuring Risk and Hazard Assessment
PhD defence
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Mitochondria in chemical-induced toxicity
PhD defence
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Chemical tools to study lipid signaling
PhD defence
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The evolution of the diversity of secondary metabolites
Why do plants produces always produced so many slightly differing metabolites within a particular chemical class?
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Molecular Cell Biology
A thorough understanding of the workings of the cell underly the understanding of disease at the molecular level. Revealing the principles of biochemical processes helps to identify the targets for the development of new drugs. At the Leiden Institute of Chemistry (LIC), we believe that the application…
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Nano shapes micro : Impacts of metallic nanoparticles on microbial communities
This thesis aimed to investigate the impact of exposure dynamics, relative contributions of ENPs(particle) and ENPs(ion), and dosing regimens on the toxicity of ENPs varying in different physico-chemical properties, on the composition and functioning of soil microbial communities.
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Nanoparticle – redox protein biohybrids
Artificial photosynthesis aims to produce fuels from solar energy using chemical processes. In semi-artificial photosynthesis, a hybrid approach is taken using both chemical and biotechnology approaches. We aim to develop hybrid systems between light-harvesting nanoparticles and redox-enzymes (oxidoreductases)…
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Dynamic hydrogels as synthetic extracellular matrices for three- dimensional cell culture
Synthetic hydrogels that mimic the natural extracellular matrix in the biophysical and biochemical cues it provides to cells are in high demand, however the cell phenotypes as they are observed in vivo in numerous cases have yet to be attained.
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Assembling anisotropic colloidal building blocks
This PhD-thesis presents a study on micron-sized particles, so-called colloids. By controlling the chemical and physical properties of these particles, such as the interparticle interaction and the particles’ shape, colloids can act as building blocks that self-assembly into larger structures.
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Bioorthogonal Antigens as Tool for Investigation of Antigen Processing and Presentation
In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…
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Leiden Institute of Chemistry
The Leiden Institute of Chemistry (LIC) is the basis for research and collaborations of the Leiden chemistry groups. Chemistry is the central science enabling a healthy future in a sustainable society. Chemistry researchers at Leiden University take a fundamental approach in finding tailored solutions…
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Energy & Sustainability
Twenty years from now, the world population is estimated to be around 8.7 billion people, compared to the current 7.3 billion. In combination with the improvements in living standards and the corresponding growth in consumption, this will result in an enormous increase in the demand for food, consumables,…
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Education
Education & outreach
- About this minor
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Back to the Present
A post-colonial approach to the concept of time in the past and present Maya culture
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The scent of the universe
Former PhD student Cameron Mackie will been awarded not one, but two dissertation prizes for his thesis on the aromatic universe. His work could provide us with a virtual sniff of space. ‘These molecules in space likely smell like a big charcoal grill!’
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Garnet Akeyr
Science
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Tanja Masson-Zwaan benoemd als officier in de Orde van Oranje Nassau
Tanja heeft zich sedert 1985 met haar bijzondere en veelzijdige talenten ingezet voor het opbouwen van het internationaal Instituut voor Lucht- en Ruimterecht, waarvan zij vanaf de oprichting codirecteur is.
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Tanja Masson: who owns the moon?
The moon exerts a pull on us. The Americans won the space race and were first to land there. In the Universiteit van Nederland, space law expert Tanja Masson explores the questions that this raises. Who owns the moon and the valuable resources that are found there?
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Space Law
Lecture, Studium Generale
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LED3 Chemical Biology Talk: Cyclic Peptides in Target Discovery
Lecture
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Chemical Weapons Use and Legal Pathways to Accountability
Conference, Seminar
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LIC Lecture: Chemically fueled droplets; towards the synthesis of life
Lecture
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Synthetic peptides as tools in chemical immunology
PhD defence
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Vici grant for research on the formation of galaxies
How do galaxies form? That is what astronomer Mariska Kriek will be researching in the coming years. She received an NWO Vici grant of 1.5 million euros to study galaxies in the early universe. ‘This research uses new and unprecedented observations from the James Webb Space Telescope (JWST). These allow…
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Chemical Biology Lecture: Vinylboronic acids in bioorthogonal chemistry
Lecture
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Chemical Tools to Illuminate N-acylphosphatidylethanolamine Biosynthesis
PhD defence
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Peptide Facility
Peptides are routinely synthesized in the range of 5-80 amino acids, in an amount of 1-200 µmol (smaller and larger amounts are also possible).
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GMP facility for innovative drugs (KFT-J10 / IGFL)
The GMP Facility facilitates development and production of Advanced Therapy Medicinal Products (ATMPs) and chemical (peptide) synthesis.
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Inhibitors and probes targeting endo-glycosidases
The chemical synthesis of inhibitors and probes targeting endo-glycosidases.
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LED3 Lecture - Elucidating inositol pyrophosphate signaling with chemical tools
Lecture
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Molecular inheritance from cloud to disk: a story of complex organics and accretion shocks
Stars like the sun are born in large molecular clouds existing from gas and dust. During the formation process, the chemical composition of the material can be altered drastically by the changing physical conditions.
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Controlled Chemotaxis
Spatially and Tempoprally Defined Microfluidics to Control Chemotactic Cells
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Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition
Diacylglycerol lipases (DAGLα and DAGLβ) convert diacylglycerol to the endocannabinoid 2-arachidonoylglycerol. Our understanding of DAGL function has been hindered by a lack of chemical probes that can perturb these enzymes in vivo.
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Research Schools
Many researchers of the Faculty of Science are members of a research school related to their area of expertise. Research schools aim at collaboration of researchers from different faculties in the same university (interfaculty schools) or in different universities (interuniversity schools).
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Giant unilamellar vesicles: An efficient membrane biophysical tool and its application in drug delivery studies
Promotor: A. Kros
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Keynote speakers
On this page you can read about our keynote speakers.
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Modulation of plant chemistry by rhizosphere bacteria
Plant-microbe interaction resulted in different physio/chemical responses by host plant and interacting rhizobacteria.