Can zebrafish provide a fast, sensitive in vivo vertebrate model for identifying novel mechanisms of Ewing sarcoma progression and for development of new anticancer compounds in a time- and cost-effective manner?

Can drug screening for tuberculosis treatment be made more efficient?

Nobody is better qualified to tell you what it is like to work at Leiden University than the employees themselves. Watch the videos and meet your future colleagues. They will be happy to share their experiences with you.

For more information regarding ongoing research projects, please contact Dr. Ilze Bot.

1. What is the exact role of PIN proteins in PAT? 2. How is PIN polarity established, and how is it modulated by AGC kinase-mediated phosphorylation? 3. What is the role of the AGC kinase, as modulators of PAT, in translating environmental signals, such as gravity, light or mechanical stress, to plant…

Imagine that you have a chronic skin condition, characterized by red patches of itchy, scaly skin. You regularly notice people staring at your skin and sense their reluctance to shake your hand. Or imagine that you have Parkinson's Disease, causing your hands to tremble and making it difficult for you…

Professors Simcha Jong (Leiden University) and Rifat Atun (Harvard University) convened an exploratory seminar to discuss challenges for health systems in realising the potential of precision medicine at Harvard University’s Radcliffe Institute for Advanced Studies in Cambridge, MA on 17 April 2017.

Inaugural Lecture

Researchers at the Leiden University Medical Centre (LUMC) have managed to culture human heart muscle cells on a massive scale. This is an exceptional achievement because it is very difficult to replicate heart muscle cells outside the body. Using a special technique, the researchers have now created…

Can we exploit the cell death machinery of the host to develop new host-directed anti-TB treatments?

PhD Defence

We examine how soil inoculation influences aboveground organisms (i) directly, and indirectly via (ii) its effects on plant chemistry or volatile emission, or via (iii) mediating the effects of belowground pathogens on aboveground organisms via the shared plant.

Which immune mechanisms are involved in host defense against Staphylococcal infection?

Can drugs that target host signaling pathways be used to eradicate antibiotic-resistant bacteria?

The Biomedical Sciences Master programme in Leiden will help to deepen and broaden your understanding of human health and disease. We provide you with a challenging and flexible programme in a personalized environment.

‘What is the best electoral system for a democracy? First prize in the Leiden University Thesis Prizes 2021 goes to someone who has added their own deftly argued vision to this socially relevant topic.’ These were the words of Annetje Ottow, president of the Executive Board and board member of the Leiden…

With this thesis the PhD-candidate aims to enrich the body of evidence concerning the relation between stress and health, and the mediating role of (un)conscious perseverative cognitions, which is captured in the extended perseverative cognition hypothesis.

Liposomes – nano-sized spheres composed of fatty molecules – are very promising for vaccination. Bio-pharmaceutical scientist Naomi Benne discovered that the immune response in animal models can be steered by varying the charge of the liposomes. She obtained her PhD degree on 8 September for this research,…

How is Pol θ responsible for T-DNA integration, and how do other DNA double-strand break repair pathways interact with Pol θ? How may we manipulate T-DNA integration to stimulate error-free integration at a predetermined genomic site?

Utilization of plant-originated products as new antibiotics

PhD Defence

Prof. Andrea Evers is a health psychologist who studies the role of behavioural factors in health and disease. As a Medical Delta Professor, she is now affiliated with Leiden University, TU Delft and Erasmus University. In that position, she conducts research at the intersection of various disciplines.…

It sounds futuristic, but it is possible: the creation of miniature organs of patients in order to study them and see how diseases develop and can be treated. This is what researchers from the LUMC, Twente University (UT), UMCG, TU Delft and the Hubrecht Institute hope to achieve in the next ten years…

Conference

What are the biological and biophysical mechanisms that control chemokine gradient sensing and migration of immune, endothelial, and tumour cells in tumour development?

The LUMC has a longstanding tradition researching the role of the immune system in infectious diseases, transplantation and auto-immune diseases.

The Faculties of Leiden University have developed several themes for research cooperation between Leiden University and its Indonesian partners.

PhD Defence

PhD Defence

PhD Defence

Research groups in the Biological & Soft Matter Programme unravel mechanisms in biological processes and develop novel bio-inspired soft materials.

How do plant defense genes get activated?

The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments. We apply our technology and methods to find biomarkers for key disease pathways and toxicity in clinical studies and in…

What are the host immune defence mechanisms that control intracellular infections and how are these subverted by pathogens?

The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments.

Promotor: M. Danhof Co-promotor: O.E. Della Pasqua

Promotor: Prof.dr. J. Kuiper, Co-promotor: Saskia C.A. de Jager

As a result of an increased life expectancy, more people suffer from chronic diseases and discomfort. Elderly patients may have multiple diseases simultaneously, with concomitant multiple medications.

Dr. Jessica Kiefte-de Jong and Dr. Thijs Bosker, both Assistant Professors at LUC, have been awarded by The Leiden University Fund (LUF).

PhD Defence

PhD Defence

How can we extend the drug residence time to combat diseases more effectively?

Lecture

Eleven Leiden researchers have been awarded a Veni grant by the Dutch Research Council (NWO). The grant will enable them to develop their research ideas for a period of three years.

This summer postdoctoral researcher Mónica Varela from the Institute of Biology Leiden was awarded a Veni grant from the Dutch Research Council (NWO). Six questions about her project and hopes for the future.