How can the development of constrictions in the blood vessels be reversed?

This research group, headed by Miranda van Eck, focusses on understanding the molecular mechanisms underlying cardiovascular and metabolic diseases. Cardiovascular disease constitutes a major health issue worldwide. Although significant knowledge has been obtained on the development of atherosclerotic…

Promotores: Prof.dr. M. Danhof, Prof.dr. D.R. Stanski

Cardiovascular disease is the number one cause of death worldwide. The most important risk factor for developing this disease is high cholesterol levels in the blood.

Promotor: J. Kuiper

Promotor: Prof.dr. J. Kuiper

Both psoriasis and atheroslcerosis are diseases characterized by a chronic and systemic inflammatory profile with local lipid disturbances that alter the barrier function of the skin (psoriasis) and cause the development of atherosclerotic plaques (atherosclerosis).

The research question is that unconscious perseverative cognition (UPC) is responsible for a considerable part of cardiovascular (CV) activity that occurs even in the absence of threats and other stressors that one may encounter in one’s daily life.

Promotores: Prof. Dr. Th.J.C. van Berkel, Prof. Dr. M. van Eck

Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.

Promotor: Prof.dr. J. Kuiper, Co-Promotor: S.C.A. de Jager

Cardiovascular syndromes are the major cause of death in Western societies.

Atherosclerosis is the main underlying pathology of cardiovascular disease. Atherosclerosis is caused by an immune response which is directed against (modified) lipoproteins which accumulate in the vessel wall.

Promotores: Prof.dr. J. Kuiper, Prof.dr. P.H.A. Quax

Despite recent advances in medicine, many devastating disorders like cancer and cardiovascular, neurodegenerative and infectious diseases still lack effective treatments. In order to address this challenge, we, as scientists from Leiden University, joined hands in the LED3 network. LED3, for Leiden…

Acute cardiovascular clinical events such as myocardial infarction and cerebral stroke represent the major cause of death in Western societies. These pathologies are primarily resulting from atherosclerosis, a progressive condition characterized by the accumulation of lipids, immune cells, and fibrous…

Childhood obesity is an increasing health issue. In the first part of this thesis comorbidities in children with obesity were studied, concerning the diagnostic process and dosing regimens.

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Promotor: M. Danhof Co-promotor: O.E. Della Pasqua

There are many complex links in the chain that provides patients with new drugs: from fundamental science, to clinical tests, to production. The entire chain can be found in Leiden. Leiden University, the Leiden University Medical Center (LUMC) and the businesses at the Leiden Bio Science Park (LBSP)…

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Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.

How do teachers’ knowledge, practices, perceptions, job satisfaction and workload in secondary education develop during a school innovation in the context of differentiated student development?

Why does social anxiety increase in adolescence and how does it grow out of control in some adolescents?

Cardiovascular disease is a major global burden and atherosclerosis is the main underlying pathological process.

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Cardiovascular disease is the leading cause of death worldwide.

Development & Disease is one of the four research themes of the Institute of Biology Leiden.

Nowadays children grow up with social media. This may influence the development of brain regions involved in social interaction. In their review article in Nature Communications, Crone and Konijn illustrate how neuroscience can contribute to a better understanding of how media and peers influence adolescents'…

This dissertation set out to provide both an integrated framework for the practices of teacher peer feedback and an in-depth understanding of teacher peer feedback in the Chinese vocational education context.

What are ‘missing links’ in research on teacher professional development trajectories? We focus on the role and development of teacher facilitators in designing and implementing (collaborative) professional development trajectories.

At LLInC, we offer many different types of training and coaching.

In her inaugural lecture on 11 September, Miranda van Eck, Professor of Cardiovascular and Metabolic Therapeutics, addressed her research related to developing medications to keep our blood vessels clean.

The proposed research program studies the impact of private foreign investment on development in Indonesia during the years c. 1910-1960.

The human body consists of hundreds, perhaps thousands of different types of cells, each with different morphologies and functions, despite having the same genome.

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How is vegetative development regulated in plants and how does this affect a plant’s life history strategy?

Education and Organisation Development

What is the relation between brain development and social and cognitive development across childhood, adolescence and adulthood?

The aim of this thesis was to develop and evaluate a Ecological Professional Development Model to support preservice biology teachers to direct their own subject-specific ecological professional development route.

This interdisciplinary minor addresses sustainabilty challenges from a systems perspective, and investigates ways to sustain society within planetary boundaries.

The University encourages you, as members of our staff, to use and develop your talents.

Law is of major importance for socio-economic development. Ideally, law organizes human interaction in a way that promotes justice and legal certainty and protects vulnerable groups from exploitation and arbitrariness.

At the division of Biopharmaceutics, we aim to develop and test new therapeutic approaches to limit or even prevent the development of atherosclerosis in order to reduce the number of acute cardiovascular syndromes such as myocardial infarction or stroke.

What is the relationship between probability experiments and cryptographic applications?