Science, Mathematical Institute (MI)

How can the development of constrictions in the blood vessels be reversed?

This research group, headed by Miranda van Eck, focusses on understanding the molecular mechanisms underlying cardiovascular and metabolic diseases. Cardiovascular disease constitutes a major health issue worldwide. Although significant knowledge has been obtained on the development of atherosclerotic…

Promotores: Prof.dr. M. Danhof, Prof.dr. D.R. Stanski

Cardiovascular disease is the number one cause of death worldwide. The most important risk factor for developing this disease is high cholesterol levels in the blood.

Promotor: J. Kuiper

Promotor: Prof.dr. J. Kuiper

Both psoriasis and atheroslcerosis are diseases characterized by a chronic and systemic inflammatory profile with local lipid disturbances that alter the barrier function of the skin (psoriasis) and cause the development of atherosclerotic plaques (atherosclerosis).

The research question is that unconscious perseverative cognition (UPC) is responsible for a considerable part of cardiovascular (CV) activity that occurs even in the absence of threats and other stressors that one may encounter in one’s daily life.

Promotores: Prof. Dr. Th.J.C. van Berkel, Prof. Dr. M. van Eck

Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.

Promotor: Prof.dr. J. Kuiper, Co-Promotor: S.C.A. de Jager

Cardiovascular syndromes are the major cause of death in Western societies.

Atherosclerosis is the main underlying pathology of cardiovascular disease. Atherosclerosis is caused by an immune response which is directed against (modified) lipoproteins which accumulate in the vessel wall.

Promotores: Prof.dr. J. Kuiper, Prof.dr. P.H.A. Quax

Childhood obesity is an increasing health issue. In the first part of this thesis comorbidities in children with obesity were studied, concerning the diagnostic process and dosing regimens.

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Promotor: M. Danhof Co-promotor: O.E. Della Pasqua

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There are many complex links in the chain that provides patients with new drugs: from fundamental science, to clinical tests, to production. The entire chain can be found in Leiden. The University, the Leiden University Medical Center (LUMC) and the businesses at the Leiden Bio Science Park (LBSP) work…

How do teachers’ knowledge, practices, perceptions, job satisfaction and workload in secondary education develop during a school innovation in the context of differentiated student development?

Why does social anxiety increase in adolescence and how does it grow out of control in some adolescents?

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Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.

Development & Disease is one of the four research themes of the Institute of Biology Leiden.

Cardiovascular disease is a major global burden and atherosclerosis is the main underlying pathological process.

Nowadays children grow up with social media. This may influence the development of brain regions involved in social interaction. In their review article in Nature Communications, Crone and Konijn illustrate how neuroscience can contribute to a better understanding of how media and peers influence adolescents'…

Cardiovascular disease is the leading cause of death worldwide.

What are ‘missing links’ in research on teacher professional development trajectories? We focus on the role and development of teacher facilitators in designing and implementing (collaborative) professional development trajectories.

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The proposed research program studies the impact of private foreign investment on development in Indonesia during the years c. 1910-1960.

How is vegetative development regulated in plants and how does this affect a plant’s life history strategy?

Education and Organisation Development

What is the relation between brain development and social and cognitive development across childhood, adolescence and adulthood?

This is a period when you may have more time to work on your personal development.

In her inaugural lecture on 11 September, Miranda van Eck, Professor of Cardiovascular and Metabolic Therapeutics, addressed her research related to developing medications to keep our blood vessels clean.

What is the relationship between probability experiments and cryptographic applications?

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The development process of any software has become extremely important not just in the IT industry, but in almost every business or domain of research.

Governance and Global Affairs, Leiden University College The Hague

Can we build a biosensor to detect neuroblastoma markers in urine using the chemotaxis system in E. coli?

This interdisciplinary minor addresses sustainabilty challenges from a systems perspective, and investigates ways to sustain society within planetary boundaries.

In the programme group Parenting, Child Care and Development we examine in what way parents (mothers and fathers) and allo-parents (e.g., professional caregivers) influence children’s development, wellbeing and health. The main focus is on children’s social-emotional development and the prevention of…

Animal Sciences’ contributions to the Development & Disease research theme include the mechanisms and evolution of embryonic development, the development of cognitive mechanisms, and animal models for understanding mechanisms of human disease.