The Hague Journal of Diplomacy is delighted to announce it will be starting its own podcast series! The series will be aimed at bringing the themes of the journal’s research off the page, and onto the discussion table. Each episode will feature a guest who will share their insights and personal experience…

Leiden biotech company In Ovo, a spin-off of Leiden University, has received a European Innovation Council Accelerator Pilot Grant. In Ovo will use this 2.5-million-euro grant in its mission to stop the culling of male chicks.

Science, Institute of Biology Leiden (IBL)

Plants are able to resist a pathogen’s attack by a dual innate immune system. The relationship between the two pathways was not clear, but it turns out that they mutually potentiate each other, as assistant professor Pingtao Ding (Institute of Biology Leiden) and colleagues (The Sainsbury Laboratory,…

Supervisor: Gerard van Westen

How to make a quantitative assessment of the relative contribution to toxicity of ions and particles? Is the toxicity of nanoparticles related to their size or shape? Which physicochemical property of nanoparticles is an appropriate dose metric of nanoparticles?

The research conducted at the Leiden Academic Centre for Drug Research is clustered within the divisions of BioTherapeutics, Drug Discovery & Safety and Systems Biomedicine and Pharmacology.

The lack of success of new CNS drugs in clinical development is in part due to the complexity of the CNS, unexpected side effects, difficulties for drugs to penetrate the brain, but also by the lack of biomarkers.

How are carbohydrates processed by the immune system? Can carbohydrates be used to trigger T-cells against other conjugated antigens? Can they be used as adjuvants?

Which metabolites of sponge are influenced by individual environmental or biological factors?

Research question

Key publications of the Systems Pharmacology group

We focus on a better understanding of the mechanisms of cancer drug resistance and metastasis.

The Leiden Academic Centre for Drug Research (LACDR) is a centre of excellence for multidisciplinary research on drug discovery and development.

This research area is focused on the development and application of novel concepts and models in the emerging area of quantitative systems pharmacology (QSP).

The Aging and Immunity group is led by Dr. Amanda Foks. In this group we aim to investigate how aged immune cells contribute to atherosclerosis and identify novel therapeutic targets and strategies to extend health span and inhibit cardiovascular disease.

Explore the unknown in order to be able to innovate in the distant future.

How do plant defense genes get activated?

On 7 September 2016, Melanie Fink and Merinda Stewart presented at a Research Forum organised by the European Society of International Law (ESIL) Interest Group on the Law of the Sea. The Research Forum took place in the framework of the Annual ESIL Conference held in Riga from 8-10 September 2016 to…

Lecture

Endocannabinoids - the body's own marijuana - are promising departure points for drug research. Professor of Molecular Physiology Mario van der Stelt examines whether inhibiting their production can be a way to fight inflammatory brain disease and to combat obesity. Inaugural lecture 19 October.

A combination of two potential drugs gives hope of a 'super blockage' of an over-active immune system, Leiden researchers report in Nature. The breakthrough came from the crystallisation of a membrane protein.

Seven talented female scientists join the fight against cancer of the Oncode Insitute. Laura Heitman of the Leiden Academic Centre for Drug Research is one of the new Junior Investigators. ‘I hope to discover new druggable targets’.

Macrophages – the front line of our immune system – protect us from infections. But in the case of the tuberculosis bacteria, this often goes wrong. The group of Annemarie Meijer from the Leiden Institute of Biology has now discovered that macrophages in zebrafish are better able to eliminate tuberculosis…

History and Religious Studies in Leiden rank # 17 and #32 in the QS World University Rankings by Subject. With this, History in Leiden ranks as the best in The Netherlands and Religious Studies ranks as second best.

On Monday 26 June Willy de Heer and Niels Blokker presented their research at the last ILS Luch Seminar before summer

Professor of Pharmacochemistry Ad IJzerman has won the Nauta Award for his years of research into signal processing proteins that are interesting for the development of new medications: G protein coupled receptors. The prize is awarded every two years for services to pharmacochemistry and chemical b…

As of 1 November, Laura Heitman has been appointed full Professor of Molecular Pharmacology at the Leiden Academic Centre for Drug Research (LACDR). Heitman has been working on the understanding and improvement of drug-receptor interactions in early drug discovery. ‘My ultimate aim is to make medicines…

As of 1 February prof. Mariëlle Bruning, dr. Stephanie Rap and Denise Verkroost LL.M. will start the second part of the research project concerning the participation of children in youth care.

On Monday 27 September 2010 Spinoza prize winners Naomi Ellemers, Ineke Sluiter, Marijn Franx (Leiden) and Piet Gros (Utrecht) announced their plans for their €2.5 million prize money. This was during the official ceremony in The Hague, at which the outgoing Secretary of State for Education, Culture…

Plant biologist Pingtao Ding, assistant professor at the Institute of Biology Leiden (IBL), has received a 2.4 million European grant from the European Research Council (ERC). This ERC Starting Grant for promising young researchers allows him to unravel the molecular mechanisms by which plants resist…

Lecture

Gerard van Westen (LACDR/division of medicinal chemistry) has been awarded with a VENI grant from NWO, the Dutch Research Council.

The new welfare state is said to be close to its citizens and does not dominate, but cooperate. “But this paradigm has a hard time to acknowledge the power relation that shapes the relation between state and citizens,” says Anouk de Koning in the interview 'The Downsides of Equality Talk in the Welfare…

To deliver a Virtual Sensor tool optimised to exploit the synergy between Sentinels 2 and 3 to allow the consistent retrieval of land surface parameters (Albedo, LAI, and LST); To extend the existing capabilities of land EO data assimilation tools to add capacity to handle data in the thermal domain…

Dong Guo was awarded two poster prizes for his poster ‘Molecular Mechanism of Allosteric modulation at G protein-coupled Receptors: Insight from a Binding Kinetics Study at the Human A1 Adenosine Receptor’ at the FIGON Dutch Medicines Days, October 6th-8th this year.

On Thursday 21 October 2021, the Europa Institute held a hybrid roundtable on the legal feasibility of financing future EU policies – such as EU Green Deal measures – through debts and of thereby extending the novel funding mechanism introduced by Next Generation EU (NGEU). This roundtable was organised…

The main subject of this thesis is the design and synthesis of paramagnetic molecules for protein studies with NMR and EPR spectroscopy.

A recent publication by Biopharmaceutics PhD-candidate Eva Kritikou has been accepted by the renowned scientific journal Scientific Reports.

The discovery in 2001 of the importance of microRNAs turned the world of molecular biology upside down. The small particles of RNA also attracted the attention of university lecturer Erno Vreugdenhil. Vreugdenhil: ‘Within five to ten years the first microRNA-directed medicines will come onto the mar…

Aim: To develop and enable application of a practical, flexible, user-friendly platform to provide the scientific community with a tool to generate land surface products and its associated uncertainties and exploit these for data-intensive science.

The idea that modern humans displaced Neanderthals because they were better protected against toxic smoke components is now under fire. An earlier study that put forward this suggestion has now been refuted by genetic research by scientists from Leiden and Wageningen. This new research was published…

Dr. Stephanie Rap, Denise Verkroost, LL.M. and prof. Mariëlle Bruning conducted a research on the participation of children in youth care in the Netherlands. In 2016 the first part, a legal desk-research on the possibilities for children to participate in youth care procedures and decision-making in…

Former PhD student Annelien Zweemer was granted the C.J. Kok Award 2014, also known as “Discoverer of the Year”. A festive ceremony took place at the Faculty’s New Year’s reception on January 6, 2015.

During the congress of the Royal Dutch Association for the Advancement of Pharmacy (Koninklijke Nederlandse Maatschappij ter bevordering der Pharmacie, KNMP) Jacqueline Gerritsen, former student Bio-Pharmaceutical Sciences at Leiden University, was awarded the KNMP student prize.

What are the behaviours of plant traits throughout various points in the growing season in a radiative transfer model framework and how well can this knowledge be integrated through data assimilation to provide priors for robust local and global vegetation products and analysis?

Two researchers at the Faculty of Archaeology have received a Veni award from the Netherlands Organisation for Academic Research (NWO). This award offers promising young researchers the opportunity to further develop their ideas for a period of three years.

Freek Janssen, a PhD-student in the department of Molecular Physiology, has received an award for the best oral presentation during the Young Medicinal Chemist Symposium organised by the European Federation of Medicinal Chemistry (EFMC-YMCS’16). Freek Janssen presented his work on “Development of Highly…