Our goal is to develop usable, practical and meaningful Brain-Computer Interfaces to diagnose, restore, repair and enhance functions of the impaired brain.

A P300-based Brain Computer Interface character speller, also known as P300 speller, has been an important communication pathway, under extensive research, for people who lose motor ability, such as patients with Amyotrophic Lateral Sclerosis or spinal-cord injury because a P300 speller allows human-beings…

We develop and test a novel and interdisciplinary approach for responsible innovation of Brain-Computer Interfaces

Always wanted to find out what zero gravity is like? Now's your chance! In December 2017 a Dutch student team will be conducting experiments during a parabolic flight, and they're looking for healthy volunteers. You do have to meet a number of strict conditions, says the team leader.

PhD Defence

The research carried out within the unit Health, Medical and Neuropsychology investigates the psychological factors of health and disease, and the development of innovative treatment.

Computer applications and quantitative methods in archaeology CAA95.

... which build on self-regulation and stress-regulation theories and considers the modification of cognitions as a mediator of therapeutic change.

Promotor: Prof.dr. S. Haring

The master’s specialisation in Clinical Neuropsychology focuses on fostering clinical and scientific skills based on a solid theoretical background as well as practical training in neuropsychology and (clinical) neuropsychological research.

Chemical reactions go hand-in-hand with an energy exchange with the environment in which they take place. Surfaces offer a variety of energy dissipation channels, constituted by the nuclear and electronic degrees of freedom of the atoms at the interface. Aiming at an improved future harvesting of energy,…

Chemical reactions go hand-in-hand with an energy exchange with the environment in which they take place. Surfaces offer a variety of energy dissipation channels, constituted by the nuclear and electronic degrees of freedom of the atoms at the interface. Aiming at an improved future harvesting of energy,…

The work presented in this thesis addresses the role of the locus coeruleus (LC) - norepinephrine (NE) system in various aspects of human cognition, and the modulation of brain state.

In the Brain and Education Lab we study the development of complex cognitive processes involved in skills such as learning, reading and math.

Brain researcher Elseline Hoekzema has discovered that the structure of the brain changes during pregnancy, particularly those areas related to social functions. These changes persist for at least two years after the mother gives birth. Publication in Nature Neuroscience on 19 December.

Laura Nijkamp’s biggest dream came true recently: she took a parabolic flight and was weightless for a moment. The BrainFly student team, which includes psychology students from Leiden, needed volunteers. She signed up immediately. She tells us all about her experience.

Nowadays children grow up with social media. This may influence the development of brain regions involved in social interaction. In their review article in Nature Communications, Crone and Konijn illustrate how neuroscience can contribute to a better understanding of how media and peers influence adolescents'…

Electrons in a crystal lattice have properties that may differ from those of a free electron in vacuum.

The more opportunities a child has to learn and develop, the stronger his or her future position in society. Leiden University investigates how the brain picks up information, and how learning processes can be influenced positively.

This study is the first to directly relate brain development to sex differences and school performance. The results debunk the myth that brain development is slower in boys.

Can playing certain games decrease cognitive decline or even enhance cognitive performance in the aging population?

Chemical biologists from Leiden, led by Dr Mario van der Stelt, have discovered substances that can reduce inflammation processes in the brain. This is a first step in the development of potential medicines for the treatment of brain diseases like Alzheimer's and Parkinson's. Published in Proceedings…

Exclusion elicits the same response in children as in adolescents and adults. That is what psychologist Mara van der Meulen found when she studied brain activity in primary schoolchildren. ‘What is new for us is that it is the same in childhood as later in life.’ Doctoral defence on 10 December.

Promotor: Prof.dr. M. Danhof, Co-promotor: E.C.M. de Lange

The factors that dynamically sculpt the inter-regional correlation of brain patterns are poorly understood. Here, we test the hypothesis that they are shaped by the catecholaminergic neuromodulators norepinephrine and dopamine.

Lecture

Dementia is a progressive disease, diagnosed at a relatively late stage when intervention may not be effective. Aim of the research is to study scans of brain networks to help discover the early network changes related to dementia. Early diagnosis may benefit effectiveness of future treatment.

What is the relation between brain development and social and cognitive development across childhood, adolescence and adulthood?

An Integrative Approach to the Hominin Record

Promotor: S.J. Edixhoven, L.D.J. Taelman

The Computer Systems, Imagery & media (CSI) research programme performs research on methods and techniques for the design, implementation and application of advanced computer systems, in particular parallel, distributed and embedded computer systems.

The worldwide race to the quantum computer is in full swing. This computer can take on computing tasks that we can only dream of today, such as finding proteins that can be used as medicines in seconds flat. Leiden physicists have discovered how the Majorana particle can be used as a building block…

The LIACS Media Lab has received a research grant from the worldwide leading graphics hardware company NVIDIA. The grant exists of newly developed hardware utilizing thousands of processors. LIACS researchers will use it to investigate deep learning in understanding imagery from sources such as MRI…

Our childhood years largely determine how we will fare later in life. In the first two decades of our life, our brain is still developing, which is clearly reflected in our behaviour. By studying how the young brain develops and how children behave, researchers can learn important information about…

In this work we describe three methods to improve the performance of Quantum Field Theory calculations.

Children and adolescents really do use their ‘smart’ brain areas. This has been confirmed by an extensive and long-running study of the brain carried out by developmental psychologist Sabine Peters . Her findings can have important consequences for education. PhD defence 27 January.

The goal of the MODOMA-project is to create a computer model of language acquisition.

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Researchers have been working for centuries in mapping the human brain. But in the year 2017 some brain structures remain still not well mapped, especially those located at the brainstem. In this paper, we quantified the test–retest reliability of imaging the brainstem nucleus locus coeruleus in vivo…

A novel mathematical model describes spatial-temporal drug distribution within one or more brain units, which are cubic representations of a piece of brain tissue with brain capillaries at the edges.

In this thesis unconventional tools based on fluidic interfaces were developed to study the surface and interfacial chemistry of graphene, to characterize the intrinsic properties of graphene, to disentangle the effects of substrate and of the environmental factors, and to improve handling protocols…

There is a link in adolescents between brain connections and impulsiveness. Leiden researchers have discovered that these connections also predict which adolescents will make more impulsive choices two years further on.

What is the relation between brain development and social and cognitive development across childhood, adolescence and adulthood?

This dissertation investigates Extended Lexical Units (ELUs), elements that are bigger than just one word and which are stored in the Lexicon.

This thesis is a collection of theoretical works aiming at adjusting quantum algorithms to the hardware of quantum computers.

This book describes the different approaches for drug delivery to the brain with an emphasis on the physiology of the blood-brain barrier (BBB) and the governing principles and concepts for drug delivery across the BBB

How is structural and functional brain development related to behavioral change in cognitive-control, impulse regulation, and socio-emotional functioning?

Cognitive processes of learning with a focus on reading comprehension and the development of mathematical skills.