Promotor: Prof.dr. R. Verpoorte, Co-Promotores: N.R. Mustafa, A.E. Schulte

The ambition to have flexible learning pathways is about creating possibilities to improve the content and form of students’ learning process, and to link learning to students’ needs. Students who have access to a flexible range of learning pathways can align their university career with their own personal…

... studies the developmental course and dynamics of cognition, self-regulation, and emotional competence, and the implications for educational and clinical practice.

Biosynthetic gene clusters (BGCs) for natural products are widespread in microbial genomes, and they are rapidly exchanged. This research assesses the factors that control the spread of BGCs and resistance genes in nature. This includes risk assessment for the spread of engineered DNA in nature.

In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.

Examining if large scale application of new energy pathways can be constrained by materials and emissions.

In this project, we aim to develop mathematical models to mechanistically and quantitatively predict the dynamics of cellular stress pathway activation and its relation with toxic effects when cells are exposed to various toxicants.

Webinar | Cleveringa Dallaire critical conversation series

Science, Leiden Institute of Chemistry (LIC)

Pathways of toxicity

Aim of the proposal is to develop lugdunomycin into a drug candidate able to treat infectious diseases caused by multi-drug resistant pathogens.

Promotor: G.P. van Wezel, Co-promotor: Y.H. Choi

What is the mechanism of action preceding a physiological effects induced by metallic nanoparticles?

Bacteria are highly complex and diverse organisms that have adapted to survive in ecological niches ranging from the most extreme to the most heterogeneous environments.

Dr. at Max Planck Institute for chemical Ecology, Jena - Germany

Focus in skin research

Is it possible for sugar patterns on cells to activate the immune system to combat cancer?

Cellular stress response pathways are activated upon exposure to chemicals and help organisms deal with various molecular dangers (e.g. oxidative stress). When these pathways become hyper-activated an adverse response takes place and cells die, which may lead to organism-level toxicity such as drug-induced…

High throughput microscopy

The Liverpool care pathway for the dying patient (LCP) is a multidisciplinary tool developed for the dying phase for use in palliative care settings. The literature reports divergent experiences with its application in a nursing home setting related to its implementation and staff competencies. The…

Promotor: Prof.dr. H.V.J. Linnartz, Co-Promotores: S. Ioppolo, H.M. Cuppen

Which microorganisms live near and inside plant roots? How do they contribute to plant health? Can microorganisms be employed in plant protection?

Both psoriasis and atheroslcerosis are diseases characterized by a chronic and systemic inflammatory profile with local lipid disturbances that alter the barrier function of the skin (psoriasis) and cause the development of atherosclerotic plaques (atherosclerosis).

Research aims: Identification of key genes involved in programming the cellular architecture of A. niger & Genetic engineering of A. niger in order to improve its secretory capacities and rheological behavior under industrial fermentation conditions.

This project aims to further understand the molecular details related to the biosynthesis and function of Galf containing glycoconjugates in fungal Aspergillus spp.

Improvisers in experimental music do not record their music in a conventional score, but in ever-changing 'tactile pathways'. This is the proposition put forward by researcher Christopher Williams. PhD defence 13 December.

Soil is a home for an unbelievable diversity and abundance of microbial life that is essential for supporting life on our planet.

We showed that constitutive and inducible chemical and morphological defenses against Western flower thrips differ between tomato and chrysanthemum plants.

Promotor: B. van de Water

Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).

In the research programme Microbial Sciences we perform state-of-the-art research in the field of biotechnology and microbial sciences.

Promotores: J.C. van Houwelingen, S.A. van de Geer

ACPA alumni Falk Hübner and Joost Vanmaele aim to put up a few signposts in the expansive field of artistic research with an article recently published on FORUM+ .

What are the developmental pathways to social anxiety (disorder), the causal processes and maintaining factors? How do these factors interact in the development of social anxiety disorder? How can this knowledge be used to design and implement effective preventive intervention programs for youth?

Exploiting metabolic vulnerabilities to identify anticancer compounds in zebrafish synthetic lethality screens.

Promotor: B. van de Water

Our research in the area of safety sciences aims to increase the mechanistic understanding of cellular toxicity of drugs and, in a broader sense, chemicals.

We aim to unravel the complex and intertwining regulatory systems that control development and antibiotic production in streptomycetes.

On Friday October 30th 2015 the sixth annual Jan Reedijk Symposium will be held. The main lectures of the day will be

Conference

Prostate cancer (PCa) is one of the most prevalent cancer in males.

The aim of this thesis is to explore the use of Bioorthogonal Antigens to study the cross-presentation pathway.

How can we manipulate the biotic and abiotic environment to increase thrips resistance in tomato and chrysanthemum? More specifically we ask: How can plant secondary metabolites that are not soluble in water be delivered to plants in seed coating or root dipping treatment? Can bacteria be used to…

Promotor: P. J. J. Hooykaas Co-promotor: B. S de Pater

Almost all bacteria are enveloped by a cell wall that provides cellular protection.

Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée