In this dissertation, matching, entropy, holes and expansions come together. The first chapter is an introduction to ergodic theory and dynamical systems.

Detection of cerebral beta-amyloid (Abeta) by targeted contrast agents remains of great interest to aid the in vivo diagnosis of Alzheimer's disease (AD). Bis-styrylbenzenes have been previously reported as potential Abeta imaging agents.

Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.

The Young Academy Leiden welcomed six new members in 2020.

In my research, we developed a method to distinguish knots. A knot is a mathematical depiction of the everyday knot that occurs in ropes and cords.

Is EEG theta\beta ratio predictive towards the negative effects of stress on cognitive performance in individuals suffering from performance anxiety? Can we improve resilience to performance anxiety by using a theta\beta ratio neurofeedback intervention?

The book Global Gold Production Touching Ground: Expansion, Informalization, and Technological Innovation is edited by Boris Verbrugge and Sara Geenen. In recent decades, gold mining has moved into increasingly remote corners of the globe. Aside from the expansion of industrial gold mining, many countries…

This project aims to explore the environmental impact of early Roman expansion (4th/3rd century BC) through a program of dating and ecological sampling of traces of field systems (centuriations).

Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel

In The Agency of Empire: Connections and Strategies in French Expansion (1686-1746) Elisabeth Heijmans places directors and their connections at the centre of the developments and operations of French overseas companies.

Why is Crossnational and Cross-cultural agents such as Henrich Carloff and Willem Leyel important when studying Early Modern expansion?

The article investigates the origins of Indo-European languages in Asia by 65 coupling ancient genomics to archaeology and linguistics.

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Leiden University has selected an architect for the realisation of its new beta-campus. As a team, Designers bureau Inbo in Rotterdam and JHK Architects have won the tender for phase 1, the new housing estate for the Faculty of Science.

Promotor: R. Tijdeman, Co-promotor: C. Kraaikamp

According to the amyloid cascade hypothesis, accumulation of beta-amyloid (Aβ) peptides initiates the pathological cascade in Alzheimer's disease (AD).

It's one of the big cosmology debates: the universe is expanding, but how fast exactly? Two available measurements yield different results. Leiden physicist David Harvey adapted an independent third measurement method, using the light warping properties of galaxies predicted by Einstein. He published…

The 18.8 million euro NWO Zwaartekracht grant for quantum software which Amsterdam, Delft and Leiden landed collectively, means for Leiden University among others the appointment of two new permanent scientific staff members, who will each form their own research group, divided among Computer Science,…

Lysosomal glycosidases are acid hydrolases that fragment glycoconjugates in lysosomes.

Promotor: Prof.dr. W.T.F. den Hollander, Prof. dr. E.A. Verbitskiy

Two new Assistant Professors are joining Science Based Business (SBB) this Autumn. ‘Xishu Li and Jian Wang are the first two Assistant Professors we recruited. This is an exciting, crucial next step for SBB,’ said Professor Simcha Jong who joined Leiden University as the Director and first Professor…

Population growth, economic expansion and the associated land use caused an increase in the number of bird species facing extinction and a reduction in carbon storage worldwide. These are the findings of an international team of scientists, also from the Leiden University Institute of Environmental…

Through the Byvanck Fund, Classical Mediterranean archaeologist Tymon de Haas has received a grant of €6,350 for his research on the ecological impact of Roman expansion. He will use this grant to investigate the traces of one of the oldest and best-preserved Roman cadastres, situated in the former…

Through the Chastelain-Nobach LUF fund, Classical and Mediterranean archaeologist Tymon de Haas has received a grant for his research on the ecological impact of Roman expansion. He will use this grant to further expand on the case-study that was made possible by the Byvanck LUF fund earlier this ye…

PhD Defence

Study Information

Study Information

Study Information

Study Information

The main focus of the thesis is the discovery and development of novel inhibitors of bacterial metallo-β-lactamases (MBLs).

How does stress influence cognitive performance? What is the role of selective attention to threatening information in this effect? Could we prevent stress-induced decline of cognitive performance with pharmacological interventions? Could we use resting state theta/beta ratio as a biomarker for cognitive…

PhD Defence

PhD Defence

PhD Defence

This paper written by Alexandre Afonso, Assistant Professor and Researcher at Leiden University, argues that gender norms and the political strength of the left were important structuring factors regarding why European countries choose migrant labour to expand their labour force in the decades that…

We simulate interstellar clouds with special plasma expansions and chemical reactions on icy dust grains to be measured in ultra-high vacuum setups. This provides the data necessary to guide and interpret astronomical observations and to model reaction networks in space. [Harold Linnartz]

In this work we describe three methods to improve the performance of Quantum Field Theory calculations.

Leiden University is involved with various grants and prizes stimulating initiatives in the field of diversity and inclusion.

PhD Defence

Four scientists will receive the TOP grant for Physical Sciences from the NWO (Netherlands Organisation for Scientific Research). They are astronomer Ignas Snellen, mathematicians Tim van Erven and Charlene Kalle and computer scientist Siegfried Nijssen. The funds will be used to finance temporary research…

The 2011 disasters precipitated widespread concern among heritage scholars about the fate of Tohoku’s cultural properties, tangible and intangible. Damage to not only buildings and landscapes but also ‘formless’ heritage, some worried, could weaken social infrastructure and thus slow or undermine re…

How geographical and institutional openness in Dutch Guiana fostered a unique colonial economy. This publication is part of the Early American Places Series.

The focus of the dissertation "Aspects of cosmic acceleration" is the study of possible mechanisms responsible for the late-time accelerated expansion of the universe.

Leiden Bio Science Park (LBSP) is the largest knowledge centre in the Netherlands in the field of life sciences & health and is also highly regarded internationally. The clustering of high-quality education, research, care and business attract students, scientists and entrepreneurs from all over the…

How did the Dutch Empire compare with other imperial enterprises? And how was it experienced by the indigenous peoples who became part of this colonial power?

Oxidation is a common degradation pathway that affects therapeutic proteins and peptides during production, purification, formulation, transportation, storage and handling of solid and liquid preparations. In the present work we review the scientific literature about structural and biological consequences…