35 search results for “autophagy” in the Public website
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Selective autophagy in host defense against mycobacterial infection
The effective treatment of tuberculosis (TB) remains a major challenge to global health.
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Functions of autophagy in the filamentous fungus Aspergillus niger
What are the functions of autophagy in the filamentous fungus Aspergillus niger?
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Inflammafish: Cross-talk between inflammation and autophagy in tuberculosis
Effective host defence against tuberculosis bacteria depends on a properly balanced level of inflammation. The Inflammafish project uses zebrafish larvae to study how autophagy controls this inflammation and vice versa.
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The role of autophagy during carbon starvation in Aspergillus niger
Autopaghy is an intracellular degradation system which targets cytosolic components to lytic compartments for degradation and recycling of the building blocks of the cell.
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Autophagy and Lc3-associated phagocytosis in host defense against Salmonella
Control of infectious diseases poses continuous challenges for human health.
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Dyslipidemia, metabolism and autophagy: antigen-independent modulation of T cells in atherosclerosis
Atherosclerosis is the main underlying pathology of cardiovascular disease. Atherosclerosis is caused by an immune response which is directed against (modified) lipoproteins which accumulate in the vessel wall.
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European network for multidisciplinary research and translation of autophagy knowledge
TRANSAUTOPHAGY is a European COST action to promote multidisciplinary research on autophagy and translation of knowledge to applications.
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Boosting the host immune system to fight tuberculosis
New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.
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INFLANET - Training European Experts in Inflammation: from the molecular players to animal models and the bedside
How is inflammation in tuberculosis controlled by interplay between autophagy and inflammasome signalling?
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The innate immune response against mycobacterial infection: analysis by a combination of light and electron microscopy
Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn, Co-promotor: Dr. M.J.M. Schaaf
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Patrick van Hage
Science
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Annemarie Meijer
Science
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Salma Balazadeh
Science
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The role of the tumor suppressor Lkb1 in energy homeostasis
The work in this thesis describes the fundamental role of Lkb1 as a conductor of metabolism-related processes in zebrafish larvae.
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Cell Wall Dynamics in Aspergillus niger
This functional genomics project aims at understanding the biology of the underlying mycelium differentiation and autolysis processes in much more detail.
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Innate immune defence against intracellular pathogens
What are the host immune defence mechanisms that control intracellular infections and how are these subverted by pathogens?
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Cell architecture and pathways for parallel secretion in the filamentous fungus Aspergillus niger
Research aims: Identification of key genes involved in programming the cellular architecture of A. niger & Genetic engineering of A. niger in order to improve its secretory capacities and rheological behavior under industrial fermentation conditions.
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ImageInLife: Training European experts in multilevel bioimaging, analysis and modelling of vertebrate development
How can novel bioimaging technologies and vertebrate model species be used to gain a better understanding of early cellular behaviours with the ultimate goal to increase our understanding of human development and disease processes?
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PhD candidate, Regulation of infection-induced inflammation
Science, Institute of Biology Leiden (IBL)
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The role of autophagy during carbon starvation in Aspergillus niger
PhD Defence
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Selective autophagy in host defense against mycobacterial infection
PhD Defence
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Cleaning up tuberculosis and salmonella infections
The cellular recycling system in zebrafish is capable of eating harmful bacteria and thus resist infections such as tuberculosis and salmonellosis. That is written by Leiden biologists from the group of Annemarie Meijer. Stimulating this form of defence could be used in new treatment methods against…
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Institute of Biology Leiden
The Institute of Biology Leiden (IBL) is an internationally oriented institute for research and education in biology. We are part of the Faculty of Science at Leiden University.
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Host-Microbe Interactions in Animal Sciences
Animal Sciences’ contributions to the Host-Microbe Interactions research theme focus on the interaction of animal hosts with pathogenic microbes but also the beneficial role of the gut microbiome.
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Zebrafish xenograft model: identification of novel mechanisms driving prostate cancer metastasis
Prostate cancer (PCa) is one of the most prevalent cancer in males.
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ZF-HEALTH - Zebrafish Regulomics for Human Health
How can zebrafish research help understanding human diseases?
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Dyslipidemia, metabolism and autophagy: antigen-independent modulation of T cells in atherosclerosis
PhD Defence
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Autophagy and Lc3-associated phagocytosis in host defense against Salmonella
PhD Defence
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New insight into tuberculosis infection
Michiel van der Vaart with a team from Leiden University and the LUMC, led by IBL-researcher Annemarie Meijer, discovered that DRAM1 is a protein that regulates anti-bacterial autophagy, a defense mechanism against infections such as tuberculosis.
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Microbial Sciences
In the research programme Microbial Sciences we perform state-of-the-art research in the field of biotechnology and microbial sciences.
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Animal Sciences
We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.
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Annemarie Meijer new training coordinator in European network
The new project INFLANET will train young scientists in Europe to become experts in inflammation research. Professor Annemarie Meijer from the Institute of Biology Leiden coordinates the training.
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IBL Symposium 2015
Conference
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This Week’s Discoveries | 11 October 2016
Lecture
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RISE Symposium 2019: Science for a Viable Society
Conference