Promotores: J.N. Kok, H.J. Hoogeboom

The main purpose of DNAmarkerpoint is to better understand the ecology, evolution and biodiversity through the study of ancient- and modern DNA.

According to a new study by an international team of researchers from the Caribbean, Europe and North America, the Caribbean was settled by several successive population dispersals that originated on the American mainland.

In the largest study of ancient DNA ever conducted, an international team of scientists has revealed the complex story behind one of the defining periods in European prehistory. The study is published this week in the journal Nature.

Identification and characterization of components of DNA repair pathways and their role in Agrobacterium T-DNA integration and repair of CRISPR/Cas induced DSBs.

A major new study of ancient DNA has traced the movement of people into southern Britain during the Bronze Age. In the largest such analysis published to date, scientists examined the DNA of nearly 800 ancient individuals. Publication in Nature on December 22, 2021.

Promotor: D. Bouwmeester, Co-promotor: D. Kraft

Dynamics of material, social and ideological relationships in the pre-Columbian insular Caribbean

The type-IV secretion system (T4SS) is a machinery able to transfer DNA and proteins between bacteria and in certain cases also to eukaryotic cells.

Our DNA molecules are packaged by proteins in compact structures. The aim of this project is to understand how modern gene editing techniques nevertheless get access to their target in the DNA.

Promotor: R.D. Gill, F. Taroni

The aim of this Research Traineeship will be to analyze the underexplored reception of ancient religions in popular culture, taking Dutch spiritual magazines as a case study. There are five such magazines: Paravisie (1986- ), Paraview (1997- ), Happinez (2003- ), Bres (1965- ), and Prana/Mantra (1975-…

Are traces of fire use detectable in ancient hominin genomes?

The genetic information of all living organisms is contained in their DNA. Cells modify the degree of DNA compaction by epigenetics, which largely determines what genes are read out and which genes are transcriptionally silent.

Promotor: P. J. J. Hooykaas Co-promotor: B. S de Pater

Irene Morfini defended her thesis on 21 February 2019

This subproject of 'From Homo Economicus to Political Animal' will be on ancient analogues for modern-day “ersatz economics”, the economics of the “man in the street”.

What is the most effective way to eliminate tumour cells? The DNA repair mechanism could play an important role in increasing the effectiveness of chemotherapy in the fight against cancerous cells. If we are to influence this mechanism, we need fundamental knowledge about how the mechanism works.

The aim of ANCIENT CHARM was to develop neutron-imaging techniques and the associated equipment, and help establish neutron imaging as a mainstream archaeological analytical technique. In particular, one of the goals was a new imaging technique which called neutron resonant capture imaging combined…

The Ancient Worlds Network brings together staff and graduate students in LIAS working on the ancient Mediterranean and Near Eastern world.

Leiden University's master’s programme in Ancient History is your opportunity to obtain a comprehensive understanding of the history of the Greek and Roman periods, with a focus on the mentality and social and economic history of the period between 400 B.C. and 400 A.D.

In the research master Ancient History at Leiden University you will study the history of the Greek and Roman period, focused on the mentality and social and economic history in the period 400 B.C.- 400 A.D.

All life on earth contains DNA, which is used to store biological information. Organisms compact their DNA in order for it to fit inside their cell(s).

Do you live in Egypt and have you always wondered about all the pharaonic heritage surrounding you? This spring NVIC organizes a beginner’s level, introductory course in Egyptology. In 6 richly illustrated lessons, the history of ancient Egypt will be brought to life, both chronologically as well as…

The areas around the Mediterranean Sea have a rich and fascinating past. Do you want to explore these ancient and diverse cultures of the Mediterranean World? In the Dutch-taught Bachelor's programme Ancient Near Eastern Studies at Leiden University you will study the world of Ancient Egypt, Mesopotamia…

Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.

The MA Classics and Ancient Civilizations at Leiden University covers the entire range of present-day research on the civilizations of Egypt, Mesopotamia, Anatolia, Syria and Palestine, Greece and the Roman Empire. In chronological terms, the program covers thousands of years, from the early origins…

Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.

Humanities, Institute for History

This project aims at investigating the multidirectional effects of forced and voluntary forms of migration in the ancient Near East.

The Classics and Ancient Civilizations (Research) master's at Leiden University covers the entire range of present-day research on the civilisations of Greece and Rome, Egypt and the Ancient Near East.

New Approaches to the Study of Textual Material from the Early Pharaonic to the Late Antique Period

Leiden physicist Maarten Kruithof has discovered how our DNA is infallibly able to fold itself and to unfold again. In his dissertation he demonstrates how DNA is folded in a single long, very flexible spiral.

As part of the NEXUS1492 project, this project will use ancient DNA techniques to shed new light on the demographic and health history of the Caribbean and the impact of European colonization on indigenous communities in the region.

Why does the past elicit this intense activity in the present? What does the past mean for the present, and what does it do to it? A WAR OF WORDS will engage this complex of Chinese claims to Manchu-Korean ancient history, South Korean reactions, public discourse and cultural expression in both states,…

Single-celled organisms have stiffer DNA than multicellular lifeforms like humans and rice. Theoretical physicists managed to simulate the folding in full genomes for the first time to reach this conclusion. Publication in Biophysical Journal on February 7.

The skin has recently gained attention within body studies for its many specific cultural and social associations, in addition to its biology. This project aims to examine the different layers of meaning and the functions invested in the skin in ancient Greece: how did ancient Greek literary and medical…

Humanities, Institute for Area Studies

This project aims to assess the risk of spread of antimicrobial resistance genes in the environment derived from currently used synthetic biology approaches in the field of drug discovery.

The wealth of shoes, sandals and other footwear from ancient Egypt is poorly understood due to lack of research. This is remarkable, because from the very beginning of Egypt’s long history footwear served practical as well as more spiritual purposes.

The Leiden Center for the Study of Ancient Arabia aims to promote research on the ancient languages and cultures of Arabia, and to disseminate this knowledge to the broader public.

In an Advance Online Publication biophysicist John van Noort and others show using magnetic tweezers that DNA is folded in compliant helices of chromatin. This allows enzymes access to the DNA needed for gene expression. Van Noort's research group made the discovery in close partnership with researchers…

Theoretical physicist Helmut Schiessel receives an NWO Projectruimte grant of 390,000 euro. He will use this budget to hire a postdoc and a PhD student to continue his research on flexibility of double stranded DNA.

Patterns of paleomobility in the Caribbean were studied through an inter-disciplinary approach using a combination of archaeological, osteological, mortuary, and isotopic data.

Fokelien Kootstra defended her thesis on 23 April 2019

This project investigates ancient water management of streams, springs and runoffs on the archaeological site of Monte Albán, Mexico, as a means to contribute with different stakeholders in the development of sustainable solutions to water problems today such as floods and scarcity.

Schneider

This monograph by dr. Kim Beerden compares Greek divination to divinatory practices in Neo-Assyrian Mesopotamia and Republican Rome.

The four possible segments A, T, C and G that link together to form DNA molecules, and with their ordering encode genetic information, are not only different in name, but also in their physical and chemical properties.