Monoacylglycerol lipase (MAGL) is the principal enzyme responsible for hydrolysis of the endocannabinoid 2-arachidonoylglycerol (2-AG). MAGL inhibition provides several potential therapeutic opportunities, including anti-nociceptive, anti-inflammatory and anti-cancer activity.

ASLU 13

Dendritic cells (DC) play a prominent role in the priming of CD8(+) T cells. Vaccination is a promising treatment to boost tumor-specific CD8(+) T cells which is crucially dependent on adequate delivery of the vaccine to DC.

Effectiveness of an early intervention program for anxiety-prone toddlers in the Netherlands

Loneliness and social isolation have become a significant problem in contemporary Japan. The financial burden associated with an ageing population has severely constrained the ability of local authorities to address the problem. As a result, policymakers have sought cost‐effective methods of tackling…

A cultural sequence of western coastal French Guiana from 5000 BP to present

Introduction to Medieval Europe 300–1500 provides a comprehensive survey of this complex and varied formative period of European history, covering themes as diverse as barbarian migrations, the impact of Christianisation, the formation of nations and states, the emergence of an expansionist commercial…

Promotor: H.J.M. de Groot, Co-Promotor: A. Alia

This fall, LUCIS will have the pleasure of welcoming Professor Hugh Kennedy from SOAS University of London to Leiden. He is the fourth Abdulaziz Saud Al-Babtain Cultural Foundation Visiting Professor in Arabic Culture at Leiden University.

The Master’s Vitality and Ageing stimulates interdisciplinary thought. Meaning that motivated students with a broad scale of Bachelor backgrounds will potentially be admitted to the programme.

The Faculty of Humanities is committed to creating an inclusive and diverse community, where all students and staff are supported, respected, and empowered to do their best work, irrespective of gender, ethnicity, sexual orientation, ability, age, religion, or socio-economic background.

Cool Little Kids is a research project that investigates the effectiveness of two programmes on the prevention and reduction of anxiety problems in shy and withdrawn children aged 2-6 years. For more information about the project please visit our Dutch website or contact us via clk@fsw.leidenuniv.n…

Leiden2022 is holding the event for young researchers from 12 to 18 September 2022: the EU Contest for Young Scientists (EUCYS).

Archaeological research of coastal farming communities on the southern North Sea coast, 2000-800 BC

Leiden is a real student city and has everything you’ll need to turn your time as a student into the time of your life

Leiden Journal of Pottery Studies 23, 2007

Promotor: D. Bouwmeester, Co-promotor: D. Kraft

The rapidly increasing commercial application of metallic nanoparticles within products will inevitably enhance the amount of NPs being released into soil.

The Western Mediterranean is a key region to understand human dispersal events within and out of the African continent as well as for the eventual replacement of Neanderthals by anatomically modern humans during the Pleistocene. Central to any conclusive interpretation of archaeological and palaeoclimatic…

Drawing on the analogical lessons of the Great War, this article uses applied history to analyze how the four parallels discerned can help us make sense of contemporary Sino-American rivalry

The research described in this thesis shows that hypercholesterolemia, a well-established risk factor for atherosclerosis, can impact skin lipid pool and barrier function already at young age. In the field of atherosclerosis, we showed that the small peptide Lyp-1 can be used as a targeting molecule…

Leiden University and the Dutch Royal Family maintain ties that go back to 1575, when William of Orange founded the University. Many members of the Royal Family have studied in Leiden and several have received an honorary doctorate.

Lithic Biographies in the Neolithic and Bronze Age, Prof. Annelou van Gijn (2010)

This Conference volume unites a wide range of scholars working in the fields of history, archaeology, religion, art, and philology in an effort to explore new perspec-tives and methods in the study of primary sources from premodern South and Southeast Asia.

It is not man’s ingenuity, but rather materials that are the source of innovation and progress. This is what archaeologist Maikel Kuijpers concludes based on his research into craftsmanship and material processing in the Early Bronze Age.

Since 2021, the Master’s programme is available to follow parttime; a parttime degree programme involving 2-3 days per week, one of which is a set, mandatory day.

From Great-Britain to the United States and from Australia to South Africa: people around the whole world speak and write English. In Leiden you will broaden your knowledge of the English language and the rich Literature and culture of the global English world on academic level.

Apps that can precisely identify shards, coins or heel bones: archaeology has embraced artificial intelligence. Alex Brandsen is working on a search engine that scans vast quantities of text from an archaeological viewpoint.

Can playing certain games decrease cognitive decline or even enhance cognitive performance in the aging population?

Music can affect how we feel, think, and behave. But how do we learn about the specifics of people's responses to music so that we can apply this to health and well-being? By looking at characteristics of the music, as well as the differences between listeners, we hope to better understand as well as…

The physical landscape is the setting in which human activities take place. Landscape and site context during human occupation is one of the areas of concern for the geoarchaeologist. A detailed stratigraphical study -both on- and off-site- clearly enhances the interpretation of the archaeologists,…

Leiden University and LUMC benefit from unique knowledge gained from research and teaching about healthy lifestyles. We want to bring this knowledge together into one place, and we want to share it even more effectively than we do now.

This dissertation examines whether a cochlear implant provides congenitally deaf born children with sufficient auditory input to acquire low salient and syntactically and semantically complex functional items such as personal pronouns compared to their hearing peers.

The main goal of the research that is conducted in the Brain and Education Lab is to create a better understanding of the cognitive and neural systems that support learning and academic performance across development. To pursue this goal, lab members draw on theories and methods from developmental and…

We have recently discovered that there are biological proteins that phase separate out of solution much the way oil will de-mix from water (see movie). These form dense, liquid-like phases called protein condensates.

Archaeobotanic research by prof. dr. C. Bakels and students on agriculture.

Can positive peer feedback break the cycle of negative self-relevant cognitive processes and reduce self-reported anxiety in early adolescents?

What is the research question?

Knowledge generated by development-led archaeology about the Late Neolithic, the Early Bronze Age and the start of the Middle Bronze Age (2850 - 1500 cal BC) in the Netherlands

How is the development of physiological responses to social evaluation in adolescence affected by other normative developments, such as pubertal, socio-cognitive and psychosocial development? Are social anxiety and public speaking anxiety associated with characteristic patterns of stress responses…

Preparatory year Leiden

Promotor: H.J.A. Rottgering, Co-Promotor: R.J. van Weeren

When doing business in foreign countries, you will encounter different languages and cultures. How does knowledge of cultural differences help you when you're trying to start a business or close a deal in another country?

In the Bachelor's programme Japanese Studies at Leiden University you will study the rich history and age-old traditions of Japan. Discover the fascinating country of haiku, samurai, geishas and manga.

An overview with the most frequently asked questions and the corresponding answers:

Young children, adolescents and students may experience learning difficulties as a result of lack of sleep. Dr Kristiaan van der Heijden investigates sleep problems and solutions for various age groups.

This master specialization offers you a combination of theories about learning problems and impairments and intervention and prevention strategies from a developmental perspective.