Zebrafish is an excellent model organism for studying various human diseases. Due to opaqueness of the adult phase, in vivo studies are restricted to early embryonic stages. This raises the need for rapid sensitive and non-invasive in vivo imaging methods to follow developmental processes, not only…

Promotores: C.A.J. Knibbe; J.N. van den Anker, Co-promotores: H.P.A. van Dongen; B. van Ramshorst

On December 11th, Andreea Geambasu succesfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Andreea on this great result.

The aim of this thesis is to expedite and ensure the systematic accuracy of clearance scaling from adults to paediatric patients, with a special focus on drugs undergoing hepatic metabolism.

Is the current existing legal framework on compulsory and voluntary care - for vulnerable young adults (between the ages of 18 to 23) - in need of revision? And if so, what kind of amendments would be advisable?

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The aim of this project is to investigate the (cost)effectiveness of two innovative forms of trauma-focused therapy for patients with childhood abuse related PTSD. The ultimate goal is to improve quality of care and contribute to treatment innovation for this severely ill target population.

Quantifying physical activity (using accelerometers) and combining the frequency and intensity of activities with health data (brain MRI, traditional clinical parameters and metabolomics) is of utmost importance to monitor mobility and health among older individuals and study health promotion during…

On Monday November 7th the research outcome ‘Involuntary (after) care for vulnerable young adults? A study to the legal possibilities for the provision of (involuntary) care to vulnerable young adults after child protection’ was presented to the members of the Parliament.

On Friday 16 April, the webinar 'Children and young adults in contact with the law: Systemic vulnerabilities and institutional responses' will take place. The webinar is organised by Eva Schmidt LL.M, Dr. Anna Pivaty (Radboud University/Maastricht University) and Dr. Stephanie Rap, with the support…

On Thursday 16 April, researchers of Leiden University, Radboud University and Maastricht University – with support of the Netherlands Network of Human Rights Research – organize an online event, titled: Children and young adults in contact with the law: Systemic vulnerabilities and institutional re…

Behavioral and neural mechanisms underlying risky decision-making in adolescents

On 16 April 2021 the webinar ‘Children and young adults in contact with the law: Systemic vulnerabilities and institutional responses’ took place. In total 17 speakers and discussants engaged with the topic of vulnerability.

PhD Defence

PhD Defence

Clearance is the most important pharmacokinetic parameter for drug dose selection. Pharmacokinetic information is typically first available in the adult population, and in general only limited pharmacokinetic data are available in children when drugs enter into the market. It is therefore of the utmost…

The prevalence of obesity (BMI >40 kg/m2) has increased rapidly over the recent years, not only in adults, but also in children and adolescents.

How can we improve quality of life and study success in young, high-functioning adults with autism?

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Lecture

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In this thesis, two potential therapeutic targets for diabetic nephropathy were dentified and investigated. First, we show that glomerular clusterin is upregulated in diabetic nephropathy and demonstrated that recombinant clusterin protein can protect the podocytes against oxidative stress in vitro.…

Everyone is welcome at the Leiden Science Family Day. We have set up a programme with a variety of activities for children, teenagers and adults.

A neurobiological perspective on individual differences in social competence

Across cultures, parents help their children master the social and linguistic codes needed in adult life. Recent research on language socialization found important cross-cultural differences, pointing out the need for more diversity for a full understanding of this process.

Platform Opleiding, Onderwijs en Organisatie Ltd (PLATO). PLATO is committed to learning, learning in schools, learning in work environments, learning in life and life.

This project introduces primary school children (8-12 years) to science and archaeology.

Childhood obesity is an increasing health issue. In the first part of this thesis comorbidities in children with obesity were studied, concerning the diagnostic process and dosing regimens.

Mapping the neural mechanisms underlying social motivations of adolescents and adults

Promotor: C.A.J. Knibbe, Co-promotor: J.J. Boelens, R.G.M. Bredius

Can playing certain games decrease cognitive decline or even enhance cognitive performance in the aging population?

We aim to keep animal testing to a minimum. We therefore assess for every study whether full account has been taken of the 3 Rs: replace, reduce, refine. The Animal Welfare Body advises researchers on this. We train our staff and provide further courses, which means we are able to continue to refine…

Education and Organisation Development

Edegar da Conceição Savio defended his thesis on 28 January 2016

Vocal learning is a trait shared by songbirds and humans. It is also a trait that is restricted by the brain rather than by a species' vocal apparatus. In this dissertation, functional MRI is employed in both species in order to explore potential common neural mechanisms underlying the ability to develop…

With an ageing population it is becoming increasingly important to find means to repair cells, tissue and organs through regenerative medicine.

Leiden University has much to offer, so why not come and visit? We’d like to meet you.

PhD Defence

Lecture

Lecture

The more opportunities a child has to learn and develop, the stronger his or her future position in society. Leiden University investigates how the brain picks up information, and how learning processes can be influenced positively.

In the animal sciences and health research theme, we work with different species of animals to learn more about fundamental biological processes.

PhD Defence

PhD Defence

PhD Defence

PhD Defence