Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. D. Tibboel (EMC, R’dam)

The major aim is to unravel the processes underlying psychological factors, such as attention and emotions, influencing the experience of itch and pain in healthy and chronic state.

The major aim is to unravel the psychoneurobiological factors, such as expectations, sensitization and attentional processes, that affect the experience of itch and pain in acute and chronic state.

The major aim is to determine the role of expectancy mechanisms (e.g., verbal suggestion, classical conditioning, and imagery) in placebo and nocebo effects on different psychical sensations (e.g., pain, itch, and fatigue) and how these expectancy mechanisms can be used to optimize health.

The disease acute myeloid leukemia (AML) is characterized by fast progression and low survival rates.

Diacylglycerol lipases (DAGLα and DAGLβ) convert diacylglycerol to the endocannabinoid 2-arachidonoylglycerol. Our understanding of DAGL function has been hindered by a lack of chemical probes that can perturb these enzymes in vivo.

PhD Defence

To what extent is “Grip op Pijn” effective and feasible in clinical practice

To relieve a patient's pain, it can be effective to induce expectations. This finding is promising for optimising the effectiveness of treatments, conclude Kaya Peerdeman and colleagues in their article in PAIN.

If you imagine in advance that something is not going to hurt, this could mean you experience less pain. This discovery was made by health psychologist Kaya Peerdeman during her PhD research on the placebo effect. PhD defence 7 February.

The €6.24 million EU-funded research project QSPainRelief has kicked off. The project aims to help patients suffering from chronic pain with novel, personalised combinational treatments and is coordinated by Elizabeth de Lange from the Leiden Academic Center for Drug Research.

Aleksandrina Skvortsova has been awarded a Rubicon grant by the NWO. She will use it to conduct research at McGill University in Canada into whether memories and stress influence how we experience pain.

Researchers at Leiden University led by Mario van der Stelt (Leiden Institute for Chemistry) have set ‘gold standards’ for developing new painkillers based on the medicinal effects of cannabis. Publication in Nature Communications.

Shell, our country's largest company, is constructing a vast plastics plant in the United States. And it is doing so at a time when the European Union, led by the Netherlands, is launching a major pact to combat use of plastic.

Shell, our country's largest company, is constructing a vast plastics plant in the United States. And it is doing so at a time when the European Union, led by the Netherlands, is launching a major pact to combat use of plastic.

If it’s up to PhD student Guangsheng Du, patients don’t need to worry about big needles anymore. At the Leiden Academic Center for Drug Research (LACDR), he studied the use of microneedles and nanoparticles as a new vaccination system. ‘I want to create a more patient-friendly delivery method.’ He defends…

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Microneedles are a promising tool for the painless administration of vaccines through the skin. But, are these minuscule needles really effective? PhD student Pim Schipper of the Leiden Academic Centre for Drug Research investigated various factors of vaccination via the skin and discovered, among other…

... which build on self-regulation and stress-regulation theories and considers the modification of cognitions as a mediator of therapeutic change.

Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver

PhD Defence

Lecture

Training and learning in the field of Health Care

Promotores: Prof.dr. J. A. Bouwstra, Prof.dr. W. Jiskoot

The Leiden Academic Centre for Drug Research (LACDR) received no less than three awards during the Figon Dutch Medicine Days. Bas Goulooze won the PhD Prize for best PhD candidate, Natalia Ortiz Zacarías and Huub Sijben both received a poster prize. ‘Scientists must be able to communicate their research…

Promotor: Prof.dr. J. Kuiper

Cardiovascular disease is the leading cause of death worldwide.

Promotor: J. Kuiper

Schistosomiasis is an acute and chronic disease caused by blood dwelling parasitic trematodes of the genus Schistosoma, and it is classified as the second most socioeconomically devastating parasitic disease, second only to malaria.

PhD Defence

Chronic stress weakens the immune system, psychologist Jos Brosschot warns in an interview with Leidsch Dagblad newspaper. Social isolation can cause feelings of insecurity and stress. He therefore advises keeping in touch with others.

PhD Defence

Liposomes hold great promise for peptide-based personalized cancer vaccination, especially when administered intradermally. However, current liposome preparation methods are very time consuming (resulting in long development times per formulation), whereas personalized cancer vaccination requires very…

To what extent do your thoughts and experiences affect your health? What is the impact of the placebo effect on medical treatments, for example for pain and itching? In this project, we will collect stories of people who have experiences with the efficacy of placebo effects, for example as a patient…

Traditionally, vaccines are administered intramuscularly using conventional hypodermic needles, which cause pain and distress. Microneedles are very short needles (smaller than 1 mm) that are practically invisible to the naked eye.

PhD Defence

PhD Defence

Collecting as much information as possible about administering a new medicine to people can save a lot of money.

The current projects of the Molecular Physiology group focus on kinases and proteins of the endocannabinoid system.