304 search results for “acute pain” in the Public website
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Acute and chronic pain after cardiac surgery
Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. D. Tibboel (EMC, R’dam)
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Role of psychophysiological factors in acute and chronic itch and pain.
The major aim is to unravel the processes underlying psychological factors, such as attention and emotions, influencing the experience of itch and pain in healthy and chronic state.
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Psychoneurobiology in itch and pain
The major aim is to unravel the psychoneurobiological factors, such as expectations, sensitization and attentional processes, that affect the experience of itch and pain in acute and chronic state.
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Placebo research: Pain and itch
The major aim is to determine the role of expectancy mechanisms (e.g., verbal suggestion, classical conditioning, and imagery) in placebo and nocebo effects on different psychical sensations (e.g., pain, itch, and fatigue) and how these expectancy mechanisms can be used to optimize health.
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Discovery of FLT3 inhibitors for the treatment of acute myeloid leukemia
The disease acute myeloid leukemia (AML) is characterized by fast progression and low survival rates.
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Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition
Diacylglycerol lipases (DAGLα and DAGLβ) convert diacylglycerol to the endocannabinoid 2-arachidonoylglycerol. Our understanding of DAGL function has been hindered by a lack of chemical probes that can perturb these enzymes in vivo.
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Pain perception and modulation in acute and chronic pain states
PhD Defence
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of an online cognitive behavioural therapy intervention for chronic pain
To what extent is “Grip op Pijn” effective and feasible in clinical practice
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Expectations can relieve pain
To relieve a patient's pain, it can be effective to induce expectations. This finding is promising for optimising the effectiveness of treatments, conclude Kaya Peerdeman and colleagues in their article in PAIN.
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Imagination can reduce pain
If you imagine in advance that something is not going to hurt, this could mean you experience less pain. This discovery was made by health psychologist Kaya Peerdeman during her PhD research on the placebo effect. PhD defence 7 February.
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The QSPainRelief consortium will improve the treatment of chronic pain
The €6.24 million EU-funded research project QSPainRelief has kicked off. The project aims to help patients suffering from chronic pain with novel, personalised combinational treatments and is coordinated by Elizabeth de Lange from the Leiden Academic Center for Drug Research.
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Rubicon grant for pain researcher Aleksandrina Skvortsova
Aleksandrina Skvortsova has been awarded a Rubicon grant by the NWO. She will use it to conduct research at McGill University in Canada into whether memories and stress influence how we experience pain.
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Jessy Terpstra
Faculteit der Sociale Wetenschappen
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Joe Blythe
Faculteit der Sociale Wetenschappen
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Pain relief without the high
Researchers at Leiden University led by Mario van der Stelt (Leiden Institute for Chemistry) have set ‘gold standards’ for developing new painkillers based on the medicinal effects of cannabis. Publication in Nature Communications.
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Jennifer Becker
Faculteit der Sociale Wetenschappen
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Shelley van der Veek
Faculteit der Sociale Wetenschappen
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Henriët van Middendorp
Faculteit der Sociale Wetenschappen
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Mia Thomaïdou
Faculteit der Sociale Wetenschappen
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Antoinette van Laarhoven
Faculteit der Sociale Wetenschappen
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Roos van der Vaart
Faculteit der Sociale Wetenschappen
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Construction of vast plastics plant by Shell: 'very painful'
Shell, our country's largest company, is constructing a vast plastics plant in the United States. And it is doing so at a time when the European Union, led by the Netherlands, is launching a major pact to combat use of plastic.
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Construction of vast plastics plant by Shell: 'very painful'
Shell, our country's largest company, is constructing a vast plastics plant in the United States. And it is doing so at a time when the European Union, led by the Netherlands, is launching a major pact to combat use of plastic.
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Tiny, pain-free vaccinations: microneedles and nanoparticles
If it’s up to PhD student Guangsheng Du, patients don’t need to worry about big needles anymore. At the Leiden Academic Center for Drug Research (LACDR), he studied the use of microneedles and nanoparticles as a new vaccination system. ‘I want to create a more patient-friendly delivery method.’ He defends…
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Bernet Elzinga
Faculteit der Sociale Wetenschappen
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Leukemia treatment & cognitive development
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Kaya Peerdeman
Faculteit der Sociale Wetenschappen
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One step closer to pain-free vaccinations
Microneedles are a promising tool for the painless administration of vaccines through the skin. But, are these minuscule needles really effective? PhD student Pim Schipper of the Leiden Academic Centre for Drug Research investigated various factors of vaccination via the skin and discovered, among other…
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Self-regulation models
... which build on self-regulation and stress-regulation theories and considers the modification of cognitions as a mediator of therapeutic change.
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Veronique de Gucht
Faculteit der Sociale Wetenschappen
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Towards understanding the toxicity of copper nanoparticles in aquatic ecosystems
Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver
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Acute myocardial infarction care
PhD Defence
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Neuroimaging of pain and distress
Lecture
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Healthcare
Training and learning in the field of Health Care
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Microneedle-mediated vaccine delivery
Promotores: Prof.dr. J. A. Bouwstra, Prof.dr. W. Jiskoot
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LACDR excels at the FIGON Dutch Medicine Days
The Leiden Academic Centre for Drug Research (LACDR) received no less than three awards during the Figon Dutch Medicine Days. Bas Goulooze won the PhD Prize for best PhD candidate, Natalia Ortiz Zacarías and Huub Sijben both received a poster prize. ‘Scientists must be able to communicate their research…
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Stress-induced modulation of the innate immune system in cardiovascular disease
Promotor: Prof.dr. J. Kuiper
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Cholesterol metabolism and hematopoiesis interaction in atherothrombosis
Cardiovascular disease is the leading cause of death worldwide.
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Circulating cells as biomarkers in cardiovascular disease : the difference between men and women
Promotor: J. Kuiper
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Synthesis and application of glycans unique to S. Mansoni
Schistosomiasis is an acute and chronic disease caused by blood dwelling parasitic trematodes of the genus Schistosoma, and it is classified as the second most socioeconomically devastating parasitic disease, second only to malaria.
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Risk and prevention of contrast induced-acute kidney injury
PhD Defence
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Psychologist Jos Brosschot in LD on how isolation can cause stress
Chronic stress weakens the immune system, psychologist Jos Brosschot warns in an interview with Leidsch Dagblad newspaper. Social isolation can cause feelings of insecurity and stress. He therefore advises keeping in touch with others.
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Intra-arterial treatment of acute ischemic stroke
PhD Defence
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Microfluidics for high-throughput liposome formulation for personalized cancer vaccination
Liposomes hold great promise for peptide-based personalized cancer vaccination, especially when administered intradermally. However, current liposome preparation methods are very time consuming (resulting in long development times per formulation), whereas personalized cancer vaccination requires very…
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Placebo Verhalen
To what extent do your thoughts and experiences affect your health? What is the impact of the placebo effect on medical treatments, for example for pain and itching? In this project, we will collect stories of people who have experiences with the efficacy of placebo effects, for example as a patient…
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Towards controlled microneedle-mediated intradermal immunization
Traditionally, vaccines are administered intramuscularly using conventional hypodermic needles, which cause pain and distress. Microneedles are very short needles (smaller than 1 mm) that are practically invisible to the naked eye.
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quality of life in painful bone metastases
PhD Defence
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Remifentanil for labour pain: safety and efficacy
PhD Defence
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Making the most of the first time a medicine is administered to humans
Collecting as much information as possible about administering a new medicine to people can save a lot of money.
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Research
The current projects of the Molecular Physiology group focus on kinases and proteins of the endocannabinoid system.