Promotor: P.J.J. Hooykaas, Co-Promotor: E.J. van der Zaal

Possible improvements for the assessment of abiotic depletion in LCA.

The overall objectives of my thesis are to investigate the dynamics of the sorghum root microbiome and to explore the beneficial effects of the root microbiome on sorghum growth and stress tolerance.

Bacterial biocatalysis constitutes a sustainable alternative for high-value chemicals production by enabling the utilization of renewable feedstocks.

The LUMC has a longstanding tradition researching the role of the immune system in infectious diseases, transplantation and auto-immune diseases.

Which compounds and microorganisms that live near and inside plant roots are beneficial? Can we use this knowledge to improve the health and growth of crop plants?

Our immune system protects us against disease, but every now and then, something goes wrong: an enemy invades our bodies or our immune system attacks our own cells and we become ill. Doctors and researchers at the Leiden University Medical Center (LUMC) want to be able to manipulate the immune system…

The Immune Activation and Tolerance group is headed by Dr. Bram Slütter. Vaccination is an experimental, but promising, treatment strategy for atherosclerosis. Previous work has shown that immunization of mice with modified LDL particles can reduce atherosclerotic lesion development, however such vaccines…

Promotor: Prof.dr. P. Hooykaas, Co-promotor: Dr. R. Offringa

This study investigates how two social and political developments, in the UK and Germany, impacted on the experiences of minorities and the attitudes of majorities vis-à-vis tolerance in those two countries. The results provide a thought-provoking picture of the views of minority and majority groups…

What is the role of stress and stress-related hormones in emotion regulation?

Does a universal psychoeducational course about stress in adolescents: I) lead to an increase in knowledge of stress?, II) affect the frequency with which stressors are experienced and the overall stress level?, III) create interest in a tier 2 level follow-up training?, and IV) appeal to students in…

The major aim is to determine the role of stress and stress-related psychophysiological mechanisms (e.g., cognitions, behaviors, and physiological stress responses) of patients with chronic inflammatory conditions and to develop and evaluate stress management interventions to alter the psychophysiological…

Factors affecting galanthamine production in Narcissus

Being a student can be stressful. Study pressure, living on your own, moving country, financial stress: things can be difficult. Unexpected difficulties may lead to study delay.

Being a student can be stressful. Study pressure, living on your own, moving country, financial stress: things can be difficult. Unexpected difficulties may lead to study delay.

All living creatures have to cope with environmental demands and threats that challenge their physical or emotional homeostasis.

With this thesis the PhD-candidate aims to enrich the body of evidence concerning the relation between stress and health, and the mediating role of (un)conscious perseverative cognitions, which is captured in the extended perseverative cognition hypothesis.

How does the endocannabinoid system in the zebrafish function at the molecular and phenotypic levels and how is it linked to the stress axis?

When we think of politics, we tend to think of adversary, antagonism, polarisation, a struggle for power. But politics should serve positive purposes, as well. Political psychologist and meditation teacher Femke Bakker (Leiden University) thinks that positive politics is first and foremost about tolerance.…

What is the effectiveness of two school-based skills-training programs in promoting mental health?

Although exposure therapy is the gold-standard treatment of posttraumatic stress-disorder (PTSD), only half of the patients adequately benefit from it. Based on recent insights into the mechanisms of extinction, this project examines strategies and techniques to improve exposure treatment outcome in…

Promotor: J.M. Memelink

Can epigenetic changes explain associations between early life stress and health outcomes?

How can we facilitate the early recognition of stress and anxiety in the classroom and collaborate with schools in providing low-threshold interventions?

Which microorganisms live near and inside plant roots? How do they contribute to plant health? Can microorganisms be employed in plant protection?

The research question is that unconscious perseverative cognition (UPC) is responsible for a considerable part of cardiovascular (CV) activity that occurs even in the absence of threats and other stressors that one may encounter in one’s daily life.

This new article by Monica Kaminska is part of a special issue for Journal of Cybersecurity, based on a selection of contributions from THe Hague Program for Cyber Norms' 2019 Conference.

Promotor: B. van de Water

Promotor: Prof.dr. J. Kuiper

What are the behavioral, cognitive, and motivational consequences of decision reversibility?

Bastiaan Rijpkema has been appointed Professor by special appointment of the new chair Tolerance at the Faculty of Humanities with effect from 1 July 2021. The chair was established by Stichting Leerstoel Uytenbogaert.

To what extent is sound a stressor to fish? And are behavioural and physiological phenotypes equally sensitive to disturbance by noise pollution?

In order to gain a better insight into the basis of the rapid jasmonic acid (JA)-mediated stress response, an integrated approach using a targeted high-resolution mass spectrometry-based (HRMS) platform, was conducted to monitor the metabolism of JA using the model system of cell suspension cultures…

What is the role of neuronal emotional reactivity in the intergenerational transmission of abuse?

Cellular stress response pathways are activated upon exposure to chemicals and help organisms deal with various molecular dangers (e.g. oxidative stress). When these pathways become hyper-activated an adverse response takes place and cells die, which may lead to organism-level toxicity such as drug-induced…

The idea that modern humans displaced Neanderthals because they were better protected against toxic smoke components is now under fire. An earlier study that put forward this suggestion has now been refuted by genetic research by scientists from Leiden and Wageningen. This new research was published…

I want to understand the overlap between physical health, mental health, and healthy aging and whether/how stress (behaviorally and biologically) may tie these concepts together.

High throughput microscopy

Fijs van Leeuwen, Professor of Radiology, Molecular Imaging and Image-Guided Therapy, advocates an open and respectful academic culture that always puts the patient first. He delivered his inaugural lecture on 13 November.

Our vision of stress is starting to change fundamentally. We can suffer stress without even being aware of it, while sleeping as wall as during the day. Professor of Psychology Jos Brosschot will discuss this phenomenon in his inaugural lecture on 2 December.

Ilze Bot and Johan Kuiper have published in The Lancet: Study unveils how stress may increase risk of heart disease and stroke. Aso: The National Dutch newspaper 'NRC' has mentioned them in a column

Promotores: T. Hankemeier; R. Berger, Co-promotor: R.J. Vreeken

The central question of this Vici proposal is to investigate if, and how actinobacteria exploit life without a cell wall.

PhD Defence

Stress, burnout, depression – these conditions pervade all levels of our society. Children and students suffer from constant pressure to achieve; at the international level, tensions lead to short-sighted actions; and, at the personal level, stress affects our health and social environment. How do our…

The Upper and Lower Houses of the Dutch Parliament are struggling with how tolerance should best be interpreted. As a result, the freedom in the Netherlands for people who hold alternative views is diminishing. This is Floris Mansvelt Beck’s conclusion on the basis of his PhD research. Defence on 2…

How does stress affect different components of behavioral impulsivity and aggression in patients with Borderline Personality Disorder compared to clinical controls (patients with Attention Deficit Hyperactivity Disorder) and healthy controls?