Identification and characterization of components of DNA repair pathways and their role in Agrobacterium T-DNA integration and repair of CRISPR/Cas induced DSBs.

Promotor: P. J. J. Hooykaas Co-promotor: B. S de Pater

How is Pol θ responsible for T-DNA integration, and how do other DNA double-strand break repair pathways interact with Pol θ? How may we manipulate T-DNA integration to stimulate error-free integration at a predetermined genomic site?

Various companies in the plant biotech industry will test a recent Leiden discovery in their crops. The ‘Pol Theta’ technology is developed in Leiden and makes it possible to reduce undesired side effects during genome engineering of plants.

The integrity and reliability of academic research are of fundamental importance to the University. All parties, both within the University and outside, must be able to have confidence that our research is conducted in a scrupulous, fair, verifiable, impartial and independent manner.

The integrity and reliability of academic research are of fundamental importance to the University. All parties, both within the University and outside, must be able to have confidence that our research is conducted in a scrupulous, fair, verifiable, impartial and independent manner. To make sure PhD…

The integrity and reliability of academic research are of fundamental importance to the University. All parties, both within the University and outside, must be able to have confidence that our research is conducted in a scrupulous, fair, verifiable, impartial and independent manner. To make sure you…

All LIAS members and visitors are kindly requested to familiarize themselves with the information provided below, to the level of detail they feel is appropriate to their situation. This information overlaps in part with the University’s web pages on scientific integrity.

Academic integrity is also an important element in the PhD track of our doctoral candidates.

Scientific integrity is an important element in the PhD trajectory, and is addressed in several different settings.

Scientific integrity is an important element in the PhD trajectory, and is addressed in several different settings.

The Academic Language Centre helps new Dutch citizens who wish to learn Dutch in the context of the Integration Act to prepare for the State Examination Programme II.

The Faculty of Science stands for research of high quality. An honest and reliable practice of science is important to us.

How should European financial law best integrate considering the interaction of the relevant legal systems?

Leiden University stands for high quality research. Integrity and reliability in the way we conduct research are core beliefs in Leiden.

Promotor: W. T. F. den Hollander, F. H. J. Redig

The database research community has made tremendous strides in developing powerful database engines that allow for efficient analytical query processing.

Integration of research and teaching is the core of Leiden University’s teaching in all programmes. The university stimulates students’ research-oriented attitudes.

Intensive public debates have erupted about integration of immigrants in Europe. The influx of refugees from the middle east during the summer and autumn of 2015, the increasing visibility of immigrants throughout European societies, but also the widely publicized occurrences on New Year’s eve in Cologne…

PhD Defence

Towards a framework that integrates content-based and process-based accounts of mathematical thinking

Corruption, integrity (or a lack thereof…) and public values are near omnipresent elements in public administration and politics of all times. Cases of corrupt public officials and politicians continuously emerge. Strangely enough, however, it often remains unknown what actually occurred, how something…

The database is created by the Centre for Public Values and Ethics of the Institute of Public Administration. Its aim is to collect and describe scandals involving (supposed) corruption and lacking integrity of public officials in the Netherlands between 1945 and the present.

This special issue of the Journal of European Policy presents results from the research on the European Union Enlargement and its Integration Capacity. The Journal of European Public Policy is one of the leading journals in this field.

This research cluster is a part of the Institute of Political Science’s research programme ‘Institutions, Decisions and Collective Behaviour’. Its members examine the sources, design, effects and contestation of norms, rules, institutionalised practices and formal organisations that operate across national…

Pathways of toxicity

C-SIDe project involves a broad selection of associates in solving cybersecurity problems. Security of software systems has emerged as a critical need in our interconnected society. Companies developing software products look for Security-by-Design approaches accommodating security into their software…

The Hazelhoff Centre for Financial Law research programme for 2020-2023 centres around the integrity of financial markets during times of crisis and possible regulation to secure it.

In the Netherlands approximately 130 out of 700 secondary schools offer a bilingual stream. However, research about CLIL (Content and Language Integrated Learning) is limited. With her dissertation Evelyn van Kampen (PhD student at ICLON) wants to contribute to the understanding of the nature and range…

This thesis describes the implementation and on-sky demonstration of high-resolution integral-field spectroscopy for extreme adaptive optics systems that are used to find and characterize exoplanets.

The cases of building materials, automobility, mushrooms and plastics.

How to bring together different footprints into an integrated family and what are the synergies? What are the roles of inventory analysis and characterization in measuring individual footprints and how these affect a footprint family? How to benchmark environmental footprints against related planetary…

What holds people together and what makes them willing to fit within larger political structures? Our project examines this question in the practices of dynastic rulership in Eurasia ca. 1300-1800.

Supervisor: P.J.J. Hooykaas

A collaboration between the IBL and LUMC has resulted in the discovery that the polymerase theta enzyme is essential for the integration of Agrobacterium T-DNA into the genome of plants. The finding means a break-through for the development of more efficient systems for targeted genome modification…

In which way and to which extent is integration articulated in concept maps and which factors affect the resulting concept maps? By which factors is the perceived usefulness of such concept maps affected?

How are night spaces imagined, produced, experienced and narrated by migrant communities in Europe? This research project considers this question in eight European cities: Aarhus, Amsterdam, Berlin, Cork, Galway, Lisbon, London, Rotterdam. Authorities have historically wrestled with the issue of night-time…

Moritz Jesse, Associate Professor of EU Law at the Europa Institute, has published his book, “The Civic Citizens of Europe: The Legal Potential for Immigrant Integration in the EU, Belgium, Germany, and the United Kingdom”.

In which way and to which extent is integration articulated in concept maps and which factors affect the resulting concept maps? By which factors is the perceived usefulness of such concept maps affected?

Cognitive enhancement reflects the use of any (legitimate) means such as for example food supplements to reach one’s personal best.

Despite the value of technology integration for educational equity and quality being emphasized by numerous studies, many gaps exist about how technology integration can be approached in policy plans, implemented in pedagogical practices, and embraced by teachers, students, and parents.

Integrating life cycle assessment (LCA) with life cycle costing (LCC) offers the opportunity to simultaneously analyze the environmental and economic aspects of product alternatives, for the integration of which a unified computational has been proposed by Heijungs et al. (2013) [1]. The project aims…

The 9th Network Europe Conference in Edinburgh was held at June 2017 in Edinburgh and organized by the Europa Institut Zurich. The contributions of the conference are now published.

The zebrafish is a promising vertebrate model organism in early drug discovery and development.

The central aims of this project are to establish the shapes of the various urban hierarchies existing in the provinces of the Roman Empire and (especially) to use the quantitative properties of these hierarchies to shed new light on levels of economic integration.

Where does Europe begin and end? How have the European Union and its precursors decided which countries are eligible to join the community and which are not? Few issues are more hotly debated, more important for the course of European integration, or more consequential for individuals in and around…

Arco Timmermans, Professor by special appointment Public Affairs at Leiden University, brought sience to practice by designing an “ideal” academic education programme on public affairs, to be embedded and taught at the graduate level.

In order to analyze the challenges linked to data use in the context of nexus governance, Giest & Mukherjee use a policy design lens and more specifically the perspective of organizational policy instruments to look at the Mediterranean region.

Promotores: W.T. de Groot, M. Tchuenté, Co-promotor: J.P. Cheylan