Promotores: Prof.dr. M. Danhof, Prof.dr. D.R. Stanski

Glycoconjugate vaccines are composed of microbial poly- or oligosaccharides covalently linked to a carrier protein.

Immunotherapies for cancer are an emerging class of therapeutic strategies which aim to treat cancer via augmentation of the immune system.

Promotores: Prof.dr. J. Kuiper, Prof.dr. P.H.A. Quax, Co-promotor: I. Bot

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. M. van der Zee

This thesis describes the design and synthesis of fragments of various cell wall carbohydrates of the Streptococcus species, including the branched Group B-specific antigen (GBC) of Group B Streptococcus, glycerol phosphate (GroP) modified group A carbohydrate (GAC), and the O-acetylated type 1 capsular…

By growing in a soil plants change the biotic and abiotic properties of the soil in which they grow.

Anthropogenic noise negatively affects wildlife in a wide range of taxonomic groups.

Promotor: Prof.dr. B. van de Water

A new publication on changes in the relationship between news and their public in Chile

Promotor: Prof. dr. Arnold Tukker & Prof. dr. René Kemp (Maastricht University)

Promotor: E.F. Smets, Co-promotor: J. Geml

Promotores: Wim Jiskoot; Ferry Ossendorp

The aim is to discover where differently shaped metal nanoparticles distributes in Danio rerio, linking the distribution with genomic responses and so come up with a Mode of Action.

Cardiovascular syndromes are the major cause of death in Western societies.

Promotor: J. van der Greef, T. Hankemeier; Co-promotor: H.A. van Wietmarschen

Promotor: B.van de Water, Co-promotor: L.S.Price

De programmagroep Onderzoeksmethoden en statistiek verzorgt het overgrote deel van het methoden- en statistiekonderwijs in alle fasen van de opleiding Pedagogische Wetenschappen. Het programma van deze opleiding is gestoeld op een sterke empirisch-analytische traditie. Dat betekent dat onderzoeksmethoden…

Religie is overal. Kennis van religie is essentieel voor iedereen die de wereld wil begrijpen. Het Leids Centrum voor Religiewetenschap (LUCSoR) bestudeert religie als een menselijke activiteit, in al zijn verschijningsvormen.

PhD defence

Autopaghy is an intracellular degradation system which targets cytosolic components to lytic compartments for degradation and recycling of the building blocks of the cell.

Because thin systems can deform along the thickness with relative ease, the interplay between surface mechanics and geometry plays a fundamental role in sculpting their three-dimensional shape.

Ontwikkelings- en onderwijspsychologie houdt zich bezig met het verloop van de ontwikkeling en de dynamiek van cognitie, zelf-regulatie en emotionele competentie en met implicaties voor onderwijs en de klinische praktijk.

Lecture, Studium Generale

Describe and identify what dosimetry parameters are of importance to interpret dose-response relationships (eg., mortality, sub-lethal, growth or reproduction inhabitation, DNA damage and reactive oxygen species, etc. ) for metal-based nanoparticles? How to develop quantitative models that enable to…

What is the optimal design of sandy solutions for sustainable climate change adaption, from an ecological, biophysical and societal point of view?

Development of scenarios for 2050 detailed in an IO framework

PhD defence

Op deze pagina vindt u het overzicht van zowel de aankomende als de afgeronde alumniwebinars van de Universiteit Leiden. Bij elk afgerond webinar vindt u de link naar de opname.

Gevolgen voor de klas en tips voor de leerkracht

Het Instituut Psychologie verzorgt innovatief en interdisciplinair onderzoek en onderwijs binnen de psychologie en aanverwante vakgebieden. Daarbij ligt de focus op drie grote gebieden: gezondheid en welzijn, ontwikkelen en leren, en sociale, cognitieve en economische besliskunde. Het onderzoek varieert…

Het Instituut Psychologie verzorgt innovatief en interdisciplinair onderzoek en onderwijs binnen de psychologie en aanverwante vakgebieden.

PhD defence

Voordrachten in het kader van het onderzoeksproject Zelfredzaamheid en sociale bescherming over de levenscyclus (aug 2017 – aug 2022).

PhD defence

Lecture

Can we distinguish the effects of pesticides from other abiotic and biotic factors that occur in the field? And how do these factors interact with pesticides?

The plant hormone auxin plays a central role in the growth and development of plants. Auxin acts in a concentration dependent manner and polar cell-to-cell transport of this hormone determines its distribution in the tissues of plants. This polar auxin transport is mediated by several families of auxin…

Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.

This thesis presents the systematics, epidermal defense, and bioprospecting of wild orchids.

As a contribution to the changing legislation and evolving societal attitudes concerning environmental issues, this project aims to enhance and manipulate the plants’ own natural defense mechanisms against western flower thrips (WFT).

Plants and their pollinators form complex interaction networks. Within these networks, species differ widely in the number of species they interact with.

Traditionally, vaccines are administered intramuscularly using conventional hypodermic needles, which cause pain and distress. Microneedles are very short needles (smaller than 1 mm) that are practically invisible to the naked eye.

On a structural level, the properties featured by a majority of mechanical metamaterials can be ascribed to the finite number of soft internal degrees-of freedom allowing for low-energy deformations.

In populations with a seed-bank, individuals can temporarily become dormant and refrain from reproduction until they can become active again. The repository of all dormant individuals in the population is called the seed-bank. Seed-banks are observed in many taxa, including plants, bacteria and other…

Op 11 juni 2020 verdedigde Sabine Witting haar proefschrift 'Child Sexual Abuse in the Digital Era: Rethinking Legal Frameworks and Transnational Law Enforcement Collaboration'. Het promotieonderzoek is begeleid door promotoren prof.mr. J.J. Sloth-Nielsen en prof.dr.mr. S. van der Hof.

1. To what extent do metallic NPs added to soil extractions change the activity, abundance, or community composition of microbes? 2. How do the effects of metallic NPs on soil microbes differ from the effects of the ions shedding from corresponding NPs?

The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.

In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…