Plants could be regarded as small chemical factories, which produce chemical substances via photosynthesis. If we can imitate photosynthesis in an artificial system, we can make clean fuels and materials out of sunlight and CO2. Huub de Groot is very close to designing a system of this kind.

Many important topics in computer science, such as the correctness of software, the efficiency of algorithms and the modeling of complicated systems, depend on sound theoretical underpinnings. In the Theory group, we study these fundamental building blocks and develop verification methods to prove system…

Treatment and care for cancer patients is becoming increasingly advanced. For example, surgeons can now perform operations with much greater precision, and therapeutic vaccines are being developed to prompt the patient’s immune system to fight cancer. Work is also being done on better early diagnostics,…

Many important topics in computer science, such as the correctness of software, the efficiency of algorithms and the modeling of complicated systems, depend on sound theoretical underpinnings. In the Theory group, we study these fundamental building blocks and develop verification methods to prove system…

Synthetic microswimmers take an important place within the interdisciplinary field of active soft matter.

Promotor: M.T.M. Koper, Co-promotor: J.B.F. Juurlink

The Pharmacy research group focusses on the development of predictive models to improve clinical drug efficacy and safety. We are moreover strongly involved in the Master specialisation of Pharmacy at Leiden University. We work on clinical problems that require further mechanistic understanding and…

Up to 50% of all children and adolescents growing up worldwide are exposed to at least one form of childhood adversity (CA), which is one of the strongest predictors for later-life psychopathology.

This third issue of Ex Novo gathers multidisciplinary contributions addressing mobility to understand patterns of change and continuity in past worlds; reconsider the movement of people, objects, and ideas alongside mobile epistemologies, such as intellectual, scholarly or educative traditions, rituals,…

Promotor: J. Schaye

Eschatology played a central role in both politics and society throughout the early modern period. It inspired people to strive for social and political change, including sometimes by violent means, and prompted in return strong reactions against their religious activism.

Metal complexes and 2D materials like graphene were combined to produce structures that can function as sensors.

In this article, Tokdemir & Klein examine the strategic actions of governments against domestic terrorist groups and domestic terrorist groups’ reactions to such actions.

This thesis describes the design, characterization and application of dextran based crosslinked network.

Advanced sensing techniques require graphene with high quality and well-controlled surface chemistry.

According to the amyloid cascade hypothesis, accumulation of beta-amyloid (Aβ) peptides initiates the pathological cascade in Alzheimer's disease (AD).

How do different emotional expressions influence the behavior of other people in negotiations?

Facts, Fears and the Future of Islamic Rules on Family Relation in the West

Observational, cognitive and physiological measurements in social contexts.

Cardiovascular disease is the leading cause of death worldwide.

The division of Drug Discovery and Safety combines the former divisions Toxicology and Medicinal Chemistry.

Several alumni, young alumni and students have been matched via the Leiden University Mentor Network.

This thesis addresses the chemical processes that determine the compositions of giant planet atmospheres.

In this doctoral dissertation (2012) the effects of the monetization of the Greek world in the 5th and 4th century on conceptions of reciprocity in friendship are analyzed.

All living creatures have to cope with environmental demands and threats that challenge their physical or emotional homeostasis.

From surface science towards industrial practice using high-pressure scanning tunneling microscopy.

The Division of Systems Pharmacology and Pharmacy (SPP) aims to develop precision medicine approaches to characterize and predict variation in treatment response and enhance translational drug development strategies.

Adverse drug reactions (ADRs) remain one of the major reasons for patient mortality and (early) drug withdrawal. Currently, different in vivo and in vitro models are used to assess the toxic potential of drugs in the pre-clinical phase. Unfortunately, the predictive value of this model does not fit…

Hydrodesulfurization (HDS) is an ubiquitous part of oil refining that ensures that fuels are cleaned of impurities and environment release of pollutants such as SOx and NOx gasses are minimized.

Promotor: Prof.dr. H.L.V. Linnartz

Consensus and harmony or balance and reciprocity?

Anthropogenic noise negatively affects wildlife in a wide range of taxonomic groups.

Promotor: H.V.J. Linnartz

Chemical reactions go hand-in-hand with an energy exchange with the environment in which they take place. Surfaces offer a variety of energy dissipation channels, constituted by the nuclear and electronic degrees of freedom of the atoms at the interface. Aiming at an improved future harvesting of energy,…

A full overview of CASC PhD theses.

Larissa Mendoza Straffon and colleagues investigated visual attentional biases toward self-made artworks, which tend to be favoured, remembered, valued, and ranked above and beyond objects that are not related to the self. Their findings confirm that attention and preference are higher for self-made…

Organic molecules in interstellar space are important as they influence the structure of galaxies and star formations. Studying catalytic processes in space allows us to understand how molecular species are formed and chemically evolved in the interstellar medium and solar system objects.

The loss of T-cell homeostasis and tolerance towards self-antigens is the underlying cause of autoimmune and inflammatory diseases like atherosclerosis, rheumatoid arthritis or type I diabetes. Traditionally, the treatment of these diseases consisted on systemic immune suppression, which can entail…

Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel

Large areas of space are filled by molecular clouds that consist of gas and dust grains that are the remnants of dead stars. When these clouds start collapsing, the decreasing temperature and increasing density cause gas particles to start accreting onto dust grain surfaces.

Research at the BPOC/SSNMR group is comprised of the following research themes:

In the research programme Drug Discovery & Safety, we are interested in the efficacy and safety of new drugs and novel means to decipher these aspects. Hence, we employ advanced imaging and high-throughput screening techniques next to computational approaches such as chem- and bioinformatics.

On 5 September 2017, Alessandro Tonutti defended his PhD dissertation