Promotor: Prof.dr. M. Danhof, Co-promotor: O.E. Della Pasqua

Overall dispersion in LCA as result of inherent uncertainties, spread and unrepresentativeness.

The Quantitative Pharmacology group headed by Coen van Hasselt focusses on the application of state-of-the-art quantitative pharmacometrics and systems pharmacology modeling combined with translational experimental models to develop personalized treatment strategies for antibiotics and to combat antimicrobial…

Quantitative biology means exploiting mathematical modelling and computer simulation as a tool to gain additional insights into the meaning of experimental data. Discover in this minor when and how to apply these tools, in a multidisciplinary setting.

This research area is focused on the development and application of novel concepts and models in the emerging area of quantitative systems pharmacology (QSP).

The Quantitative Clinical Pharmacology group is led by Prof. Dr. Catherijne Knibbe. Her research group aims to define how to adjust a drug dose in special patient populations such as (prematurely born) neonates or children, obese individuals or critically ill patients. Through combining the statistical…

Antimicrobial drugs constitute a fundamental part of modern medicine. The global rise in antimicrobial resistance poses a major threat to global health.

Brownian motion is the random motion of (colloidal) particles due to collisions with the atoms and molecules of the solvents, which are moving due to temperature.

What performance criteria does a new technology have to fulfill in order to be added to the list of future energy options and what constraints exist in terms of broad market penetration?

Promotor: T. Schmidt

Promotor: Prof.dr. G.R. de Snoo, Co-promotor: R. Heijungs

In higher education intermediate assessment is used in different ways. In her PhD research Indira Day shows that lecturers should be able to continue to have the freedom to use various test forms, because not one type of test is optimal.

What is the environmental impact, the human health impact and the life cycle and production costs of the lab, pilot and commercial diffusion of nanowires and nanowire-based photovoltaic technologies?

In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.

Just as in phase 1, phase 2 of the Gorlaeus Building will focus on sustainable building.

Several buildings need to be demolished to make way for phase 2.

In this dossier you can read about Leiden University’s commitment to sustainability.

PhD defence

What are the key issues in conducting LCA of bioenergy systems? What is the environmental sustainability status of second generation bioethanol? How much would the final results of biogenic carbon neutrality assumptions deviate from the true values based on a complete inventory? How to assess the impact…

Promotores: Prof.dr.G.R. de Snoo and Dr. R. Heijungs

Are there significant differences among the environmental impacts resulting form the production of Asian aquaculture commodities and what are the main causes for these?

Leiden University takes its place at the heart of society seriously, and the university is committed to helping build a sustainable society. Making buildings more sustainable contributes to achieving Dutch and European environmental standards. Leiden University takes this into account in all its building…

Promotor: Prof.dr. W.J.G.M. Peijnenburg, Co-promotor: Dr. ing. M.G. Vijver

Leiden University is a integral part of the community and contributes to a sustainable society. Over the coming years our University will become even greener.

How can we organise society so as to keep our planet habitable for us and for all other life forms around us? To answer this question, Leiden researchers collaborate across disciplines, from biology to data science, and from environmental economy to archaeology.

Some examples of research questions include: What framework of circular strategies should local practitioners use? How should practitioners organize their monitoring of the circular economy activities in the region of interest? What are the main products that have the most circular potential in the…

To safeguard the quality of research within Leiden University, a committee of external experts evaluates the University’s institutes once every six years according to the Standard Evaluation Protocol which is drawn up by the Association of Universities in the Netherlands (VSNU), The Royal Netherlands…

What is the environmental impact of different waste collection systems across Europe? How can the collection be improved when considering collection, sorting, and treatment, as well as use options for secondary materials?

The availability of complete plant genome sequences together with the ever increasing amount of data on the molecular, cellular and physiological mechanisms of plant development require mathematical and computational models to obtain a complete overview of and generate new insights into the quantitative…

Exploring linkages between energy and material use and implications for sustainable development.

In-use stocks of products can be considered as intermediaries between human needs and the physical world.

Review Committees, with cross-boundary experts, are invited to assess our research and education programmes. All our research will be evaluated once every six years, based on the national evaluation system for publicly funded research in the Netherlands.

How can formative assessment be used to promote teacher professional learning? This book contains various studies into professionalization approaches and courses in which formative assessment is used with a view to teacher learning.

How can prospective LCA be streamlined in a way that its practical application in research and technology development increases?

During the development of the Humanities Campus, as many 'green choices' as possibile are being made. This concerns the buildings as well as the surrounding area. Making the campus more sustainable is measured using the BREAAM.NL method.

In early 2019, the QANU (Quality Assurance Netherlands Universities) published its Report on the Research Review of Leiden University Centre for Linguistics (LUCL). This review takes place every 6 years as part of the overall monitoring and safeguarding of research quality in the Netherlands.

Following their application to system biological models, control theory techniques have further potential to aid in the understanding and application of quantitative systems pharmacology models.

Creating a framework to assess the sustainability of fish farms which will set sustainability standards and give consumers information about the the sustainability and safety of their seafood.

Describe and identify what dosimetry parameters are of importance to interpret dose-response relationships (eg., mortality, sub-lethal, growth or reproduction inhabitation, DNA damage and reactive oxygen species, etc. ) for metal-based nanoparticles? How to develop quantitative models that enable to…

The Leiden University Sustainability Network is the platform for Leiden University staff to combine their efforts and support each other in making our university more sustainable.

As part of the process of safeguarding the quality of our research, our institutes are audited regularly by a committee of external experts.

During the development of the Humanities Campus, many aspects of sustainability are combined. For example:

The moment is there: LUGO can finally announce the winner of the Sustainability Award 2020!

The moment is there: LUGO can finally announce the winner of the Sustainability Award 2020!

Twenty years from now, the world population is estimated to be around 8.7 billion people, compared to the current 7.3 billion. In combination with the improvements in living standards and the corresponding growth in consumption, this will result in an enormous increase in the demand for food, consumables,…

How to make a quantitative assessment of the relative contribution to toxicity of ions and particles? Is the toxicity of nanoparticles related to their size or shape? Which physicochemical property of nanoparticles is an appropriate dose metric of nanoparticles?

In the Governance of Sustainability programme you learn to become a future ‘change maker’ who is able to develop governance solutions to major and complex environmental sustainability challenges.

We study cell-fate decision-making using embryonic stem cells as a model system. Stem cells integrate a large number of cues to direct their development into a great variety of cell types.

PhD defence