1,652 search results for “probabilistic graphical models” in the Public website
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Developing metabolomics for a systems biology approach to understand Parkinson's disease
Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…
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Dynamical Gibbs-non-Gibbs transitions and Brownian percolation
Promotor: Prof.dr. W.Th.F. den Hollander, Co-promotor: R. Fernandez.
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Studies on molecular basics of metabolic syndrome in zebrafish
The research described in this thesis has, using the zebrafish as a model system, shed new light on the intricate relationship between TB and DM2, in particular on the role of leptin, SHP-1 and glucocorticoids.
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Patterns on Spatially Structured Domains
We consider the propagation of electrical signals through nerve fibres.
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Galaxy alignments from multiple angles
Galaxies form and live inside dark matter haloes. As a consequence, they are exposed to the tidal fields generated by the surrounding matter distribution: this imprints a preferential direction to the galaxy shapes, which leads to a coherent alignment on physically close galaxies, called intrinsic a…
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Non-equilibrium chemistry and cooling in simulations of galaxy formation
Promotor: J. Schaye
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Zipping into Fusion
Promotor: Prof.dr. J.G.E.M. Fraaije, Co-promotor: A. Kros
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Radio galaxies near the epoch of reionisation
This thesis explores the theoretical and observational properties of distant massive galaxies that harbour active black holes in their centres and shine brightly at radio wavelengths.
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The innate immune response against mycobacterial infection: analysis by a combination of light and electron microscopy
Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf
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Pharmacology based toxicity assessment: towards quantitative risk prediction in humans
Promotor: Prof.dr. M. Danhof
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Improving robustness of tomographic reconstruction methods
Promotor: Prof.dr. K.J. Batenburg
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First-pass and systemic metabolism of cytochrome P450 3A substrates in neonates, infants, and children
Growth and development affect the metabolism of drugs administered to neonates, infants, and children.
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SMALL Savannah : an information system for the integrated analysis of land use change in the Far North of Cameroon
Promotores: W.T. de Groot, M. Tchuenté, Co-promotor: J.P. Cheylan
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Atomic Insights into Hydrodesulfurization
Hydrodesulfurization (HDS) is an ubiquitous part of oil refining that ensures that fuels are cleaned of impurities and environment release of pollutants such as SOx and NOx gasses are minimized.
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Impact of low-carbon electricity development on carbon emissions in China
Low-carbon (LE) technologies have a significant potential to reduce the total carbon emissions in China.
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Interactive scalable condensation of reverse engineered UML class diagrams for software comprehension
Promotores: Prof.dr. J.N. Kok, Prof.dr. M.R.V. Chaudron (Chalmers Univ., Sweden)
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Gibbs-non-Gibbs transitions and vector-valued integration
Promotor: W. T. F. den Hollander, F. H. J. Redig
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Surf Innovation Challenge Awards voor Shabaz Sultan en Simon Portegies Zwart
Shabaz Sultan en Simon Portegies Zwart, met de hulp van Vincent Icke, hebben één van de tien Surf Innovation Challenge Awards gewonnen voor hun onderzoek naar 'Interactive high-performance laboratory for Chaos'. De winnaars hebben een geldprijs van 10.000 euro ontvangen en krijgen 6 maanden (tot 1 juni…
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Determining the most appropriate dose metrics for evaluating dose-response relationships of metal-based nanoparticles to Zebrafish embryos
Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver
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Microcoil MRI of Plants and Algae at Ultra-High Field: An exploration of metabolic imaging
This thesis investigates the relations between metabolism and anatomy through the use of Magnetic Resonance Imaging (MRI).
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The Metals Programme
Accumulation of metals in economy and environment and its associated risks, within the Netherlands and the EU.
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Anna Latour wint tweede prijs bij KNVI Scriptieprijs voor Informatica
De Koninklijke Nederlandse Vereniging van Informatieprofessionals (KNVI) reikt Scriptieprijzen voor Informatica en Informatiekunde uit
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Understandig Sponsorship Involvement Outcomes in Partnership Models
PhD Defence
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Assistant professor in process-based ecotoxicology (0.8-1.0 fte)
Science, Institute of Environmental Sciences (CML)
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The Role of Collective Redress Actions to Achieve Full Compensation for Violations of European Union Competition Law
Op 23 juni 2019 verdedigde Zygimantas Juska zijn proefschrift 'The Role of Collective Redress Actions to Achieve Full Compensation for Violations of European Union Competition Law'. Het promotieonderzoek is begeleid door promotor prof. dr. T.R Ottervanger.
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Vaccination and Targeted Therapy Using Liposomes; Opportunities for Treatment of Atherosclerosis and Cancer
This thesis focuses on using liposomes in two different treatment strategies; vaccination (or immunotherapy) and delivery of a small molecule, and in two different disease models; cancer and atherosclerosis.
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Lipids as therapeutic targets for barrier repair in skin diseases
The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.
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On the Emergence of the Energy Transition
The energy system is at the heart of two of the greatest challenges of the 21st century: decreasing CO2 emissions to meet the ambitions of the Paris agreement while fulfilling the growing energy demand associated with the economic aspirations of a growing world population.
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Motivatie ontrafeld: waarom blijven armoede, onrecht, discriminatie en zelfs genocide de mensheid teisteren?
Naar motivatie wordt al 100 jaar onderzoek verricht. En dat is niet verwonderlijk, want motivatie ligt aan de basis van ons bestaan. Waarom doen we de dingen die we doen? Waarom willen we iets, of stellen we juist uit? Maar ook in grote dingen: waarom worden we verliefd, kopen we een huis, starten we…
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Zebrafish as vertebrate model of Gaucher disease
PhD Defence
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Vondel en Vergilius: model voor een carrière
Lecture
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Abstract Behavioral Specification: unifying modeling and programming
PhD Defence
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On metrics and models for multiplex networks
PhD Defence
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Models of Nonlinear and Stochastic Astrochemical Kinetics
PhD Defence
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Programmanormen
Het project programmanormen bevat richtlijnen voor de inrichting van het onderwijs van de Faculteit der Geesteswetenschappen
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‘Investeerdersrisico belemmert de energietransitie’
Met de huidige marktregels is het behoorlijk risicovol om in groene energie te investeren, en dat staat de strijd tegen klimaatverandering in de weg. Dat schrijft milieuwetenschapper Oscar Kraan in zijn proefschrift. Promotie op 25 april.
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Data Driven Modeling & Optimization of Industrial Processes
PhD Defence
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Research scientific programmer, Automated machine learning for spatio-temporal Earth Observation datasets
Science, Leiden Institute of Advanced Computer Science (LIACS)
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Improved hard real-time scheduling and transformations for embedded Streaming Applications
This thesis addresses the problem of designing performance and energy efficient embedded streaming systems, that is, systems which process a stream of input data coming from the environment and generate a stream of output data going into the environment.
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Breaking & Entering: PAH photodissociation and top-down chemistry
Laboratory, observation and modeling work on the dissociation of polycyclic aromatic hydrocarbons in interstellar environments and the formation of new molecular species through the fragmentation process.
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Towards circular and energy-efficient management of building stock
Material circularity and energy efficiency are highly relevant and intertwined issues for the transition towards a carbon-neutral and circular built environment. In the Netherlands, the building sector has been rendered a priority towards a circular and low-carbon society.
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Workshop: Metalearning and model management for data science
Lecture
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Computational modeling of angiogenesis: from matrix invasion to lumen formation
PhD Defence
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Current challenges in statistical DNA evidence evaluation
Promotor: R.D. Gill, F. Taroni
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Me, My Fiends, and I
A neuro-ecological perspective on adolescent prosocial development
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Probing Gravity at Cosmic Scales
The theoretical explanation of cosmic acceleration is nowadays one of the biggest puzzles in cosmology.
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Aspects of cosmic acceleration
The focus of the dissertation
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Towards a system-based pharmacology approach to predict developmental changes in renal drug clearance in children
Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)
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Making the invisible visible: paramagnetic NMR and the transient protein complex
Promotor: Prof.dr. M. Ubbink
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Pattern mining for label ranking
Promotor: J.N. Kok, Co-promotor: C.M. Soares, A.J. Knobbe