We focus on natural products research, traditional medicine, ethnobotany and phytochemistry.

Streptomyces present a valuable platform for natural product discovery. Lugdunomycin is a novel angucycline-derived polyketide from Streptomyces sp QL37, with unprecedented skeleton and antimicrobial activity.

Creating information portals for support of European environmental policy.

As a contribution to the changing legislation and evolving societal attitudes concerning environmental issues, this project aims to enhance and manipulate the plants’ own natural defense mechanisms against western flower thrips (WFT).

Development of an aggregated impact indicator to measure decoupling.

The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.

The multiple connections between emblematics and Natural History in the broader perspective of their underlying artistic, literary, political and religious ideologies.

- Which metabolites could be components of NADES? - How can we prove the presence of NADES in nature? - What are the roles of NADES in nature? - How to apply NADES in life sciences?

This research network aims to create a shared platform for debate and dialogue on the broader theme of cultural production and exchange across different area specializations and historical periods.

Through his project we will unravel the global regulatory networks that control gene expression in Streptomyces bacteria and allow them to properly respond to major changes in the environment; we will then harness this knowledge to activate and identify novel antibiotics

Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).

Utilization of plant-originated products as new antibiotics

Bacteria are highly complex and diverse organisms that have adapted to survive in ecological niches ranging from the most extreme to the most heterogeneous environments.

Loneliness and social isolation have become a significant problem in contemporary Japan. The financial burden associated with an ageing population has severely constrained the ability of local authorities to address the problem. As a result, policymakers have sought cost‐effective methods of tackling…

Streptomyces bacteria are a valuable source of natural products, many of which are used in the clinic or in biotechnology.

European product safety law is one of the focal points of internal market legislation.

Central to the research of several cluster members are the social function and contexts of the production and consumption of medieval and early modern art, literature and media:

Promotor: Prof.dr. C.A.M.J.J. van den Hondel, Dr. ir. V. Meyer, Co-promotor: Dr. A.F.J. Ram

Research in the natural computing group covers theoretical foundations, the development of new algorithms, and interdisciplinary applications of natural computing methods.

How citizens and professionals are the key to successful collaboration in the delivery of public services. How do individual characteristics of citizens and professionals influence citizen-professional collaboration in the co-production of public services?

Promotor: S.M. Verduyn Lunel, Co-promotoren: M.F.E. de Jeu, S.D. Silvestrov

Here you can find products and research tools developed by the Navigation Lab Leiden

Electrolysis is a technique that can be used to convert CO2 into fuels and other useful products. To do this efficiently and on a large scale, however, we need to understand exactly how electrolysis works. Professor Marc Koper is an expert in this field.

How can we make the production of chlorine cheaper and more friendly for the environment?

The Netherlands is not particularly rich in ‘wild nature’. Comparatively, what we have is a lot of intensively used agricultural land. This means that from nature’s perspective there much to be gained by combining the ‘nature’ and ‘agriculture’ functions. Not an easy task in such a densely populated…

In this thesis we study products of linear error correcting codes.

Lecture

Can zebrafish larvae be used as a behavioural model for screening natural products as potential neurotropic drugs?

Promotor: Prof.dr. F.S. de Boer, Co-promotor: D. Clarke

Lecture

This dissertation is a study of the view of the Neoplatonist Proclus (Athens, 411-485) on to what extent and how the changing and unreliable world of sense perception can itself be an object of scientific knowledge.

Research practice, funding agencies and global science organizations suggest that research aimed at addressing sustainability challenges is most effective when ‘co-produced’ by academics and non-academics. Co-production promises to address the complex nature of contemporary sustainability challenges…

Can the pink-pigmented microbe Methylobacterium extorquens be genetically engineered to convert the sustainable raw material methanol into antibiotics?

Promotor: Prof.dr. J.P. Abrahams

Natural Computing investigates algorithms and phenonema based on nature to create better and new computer science innovations.

Science, Institute of Biology Leiden (IBL)

A neural network mimics how our brain works. Evolutionary algorithms use the principle of natural selection to solve complex problems. This kind of 'natural computing' is being used to improve the diagnosis of Parkinson's disease or the production of steel.

Factors affecting galanthamine production in Narcissus

Promotor: A. Doelman, Co-promotores: P.J.A. van Heijster; A. Zagaris

It is well-known that humans have significantly transformed ecosystems since their adoption of agriculture. However, in a deeper past, prehistoric hunter-gatherers may already have altered and modified their niche in ways that had major impacts on ecosystems.

The Hydrogen network brings together leading researchers from different disciplines and sectors with a combined expertise that maximises the chance of achieving scientific breakthroughs in production and storage of hydrogen, while guaranteeing the successful training of a new generation of scientists…