In photoactivated chemotherapy (PACT), a biologically active compound is caged by a light-cleavable protecting group.

On the 4th of June, Saskia Lensink successfully defended a doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Saskia Lensink on this achievement!

Gibbs processes, g-measures, fuzzy Gibbs states

Promotor: H.J.M. de Groot, Co-Promotor: A. Alia

A technique originally developed for satellite imaging can now be used to recover pictographic texts from underneath the surface of a five hundred year old Mexican manuscript.

Imaging and Imagining Palestine is the first comprehensive study of photography during the British Mandate period (1918–1948).

Which immune mechanisms are involved in host defense against Staphylococcal infection?

This thesis aims to demonstrate how the achromatic nature and design flexibility of liquid-crystal optics can be used to improve high-contrast imaging instruments to facilitate detailed exoplanet characterization.

Making choices is part of life. You make larger or smaller choices in everything you do, and you progress from one choice/decision to the next. All decision-making processes involve three aspects: making a choice, experiencing that choice and reflecting on it.

The purpose of this study was to investigate the formation and growth kinetics of complexes between proteins and oppositely charged polyelectrolytes.

The Animated Image addresses the entire range of contexts in which images were described by Roman authors as being animated, as well as the accounts that Roman writers produced to explain the animation of inanimate matter.

Analysis of drug adversity

This project examines how speakers store and process regular pitch variation.

.

In Film and Video Intermediality, Janna Houwen innovatively rewrites the concept of medium specificity in order to answer the questions “what is meant by video?” and “what is meant by film?”

The transition period in which men become fathers might provide an important window of opportunity for parenting interventions that may produce long-term positive effects on paternal care and, consequently, child development. Existing prenatal programs traditionally focus on maternal and infant health…

Real-life processes are characterized by dynamics involving time. Examples are walking, sleeping, disease progress in medical treatment, and events in a workflow.

Fish climbing trees, storks taking care of their parents… Premodern textual and visual culture presents us with a fabulous bestiary that reveals ingenious and rich reflections on the animal kingdom.

Bispecific antibodies with one Fab arm binding to effector cells, such as T-cells and NK-cells, while the other Fab arm recognizing a tumor associated antigen (TAA) can be used to redirect these effector cells for tumor specific killing. Using bispecific antibodies to treat hematological cancers is…

Compact Cinematics challenges the dominant understanding of cinema to focus on the various compact, short, miniature, pocket-sized forms of cinematics that have existed from even before its standardization in theatrical form, and in recent years have multiplied and proliferated, taking up an increasingly…

In this thesis we investigated the ability of two-photon multifocal microscopy for single-molecule microscopy in live cells and organisms.

Smartphone behaviors are so common but how does the brain generate this behavior? The Cognition in the digital environment laboratory (CODELAB) investigated the brain activity surrounding smartphone interactions with the help of Artificial Intelligence. According to their research, the brain fluidly…

How can the importance of the image in late medieval spirituality be understood in the context of the love mysticism inspired by the imagery of the Song of Songs?

This project looks at how the native language influences processing mechanisms of non-native language(s) as well has how it influences brain structure and functional connectivity.

Promotor: S.M. Verduyn Lunel, Co-Promotores: S.C.Hille, O.W. van Gaans

PURPOSE: To monitor the biodistribution of IgG1 aggregates upon subcutaneous (SC) and intravenous (IV) administration in mice and measure their propensity to stimulate an early immune response.

Promotor: E.F.A. Deprettere, Co-Promotor: A.C.J. Kienhuis

Legitimacy is generally a term that is associated with the state. The term surfaces when there are problems with state legitimacy—when it is lacking or absent. This present volume attempts to think through the relevance of the concept of legitimacy for other political actors than the state.

This project is aimed at 1) elucidating the role of attention in itch and pain, including orientation, and attentional disengagement (i.e., directing attention away) from itch and pain; and 2) modifiability of these attentional processes.

The main theme of this thesis is the theoretical study of Gaussian processes as a tool in Bayesian nonparametric statistics.

To what extent and how do identity processes influence health behavior?

Basketry, cordage and textiles made of plant fibers or bark are rarely preserved in the archaeological record. By means of experimental archaeology and microwear analysis, we obtain indirect evidence about this important craft.

People who have taken antibiotics in the past three months pay more attention to negative facial expressions, according to research by postdoc Katerina Johnson and assistant professor Laura Steenbergen. This may explain how antibiotics increase the risk of developing depression.

In this thesis, the focus lies on studying glucocorticoid receptor dynamics in living cells with the aim of understanding how this transcription factor finds its DNA target sites to regulate transcription.

The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.

The elementary excitations of magnets are called spin waves, and their corresponding quasi-particles are known as magnons. The rapidly growing field of Magnonics aims at using them as information carriers in a new generation of electronic devices, (almost) free of electric currents.

Reasserting America in the 1970s brings together two areas of burgeoning scholarly interest.

PhD defence

How does task context affect children’s word productions?

LUMC researcher Marius Staring will receive a $ 200,000 grant from the Chan Zuckerberg Initiative to improve the accessibility, interoperability and efficiency of the Elastix imaging software. This will give the popular 2003 software package a much-needed new impulse.

This book provides a comparative analysis of the process of breach across ten different European jurisdictions by identifying and elaborating a number of key analytical themes through which the different systems can be compared and evaluated.

The group Theoretical Physics of Life Processes, led by Helmut Schiessel, focuses on the physics of chromatin, the DNA-protein complex that fills the nuclei of eukaryotic cells.

Business Process Model and Notation (BPMN) has become the standard for business processes diagrams.

-

Promotor: Prof.dr. B.R. Katzy, Co-promotor: R. Ortt

What holds people together and what makes them willing to fit within larger political structures? Our project examines this question in the practices of dynastic rulership in Eurasia ca. 1300-1800.

Are you interested in one of our vacancies? To get to know each other well, we follow a number of steps in the application process.

In this project, we plan to combine two strands of research in speech processing: (a) the impact of prosody on speech processing and (b) the impact of musical training on speech processing. In our project we will test 8 year-old children with different degrees of musical training: (a) primary school…