How do nanoparticles bioaccumulate and biodistribute in organisms?

A critical look at the impact assessment modelling of metals in Life Cycle Impact Assessment and improvement options.

Description of The Regional Network on the Synergy between the Convention on Biological Diversity and the UN Convention to Combat Desertification.

Science, Leiden Institute of Physics (LION)

Hoe kun je vergelijkingen oplossen die niet ‘slechts’ een curve beschrijven, maar ook tweedimensionale oppervlaktes of zelfs objecten met nog meer dimensies? Dat is de grote vraag die wiskundige Martin Bright en zijn team gaan proberen te beantwoorden. Ze krijgen hiervoor een NWO Science-XL subsidie…

This monograph focuses on clustering of objects in high-dimensional data, given the restriction that the objects do not cluster on all the attributes, not even on a single subset of attributes, but often on different subsets of attributes in the data.

Multi-objective evolutionary computation aims to find high quality (Pareto optimal) solutions that represent the trade-off between multiple objectives.

Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel

Can we distinguish the effects of pesticides from other abiotic and biotic factors that occur in the field? And how do these factors interact with pesticides?

In the last decade, the redox interconversion between metal thiolate and disulfide compounds has been extensively investigated for copper, but not for other transition metal ions.

This thesis aims to enhance our understanding of galaxies by testing theoretical models of galaxy formation against observations, particularly in the cases of extreme systems which have been found to have an excess of baryonic mass in their central regions, in the form of either supermassive black holes…

Promotor: G.P. van Wezel, Co-promotor: Y.H. Choi

The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.

Promotores: Prof.dr. F. van Lunteren, Prof.dr. F.S. Gaastra

A P300-based Brain Computer Interface character speller, also known as P300 speller, has been an important communication pathway, under extensive research, for people who lose motor ability, such as patients with Amyotrophic Lateral Sclerosis or spinal-cord injury because a P300 speller allows human-beings…

To gain more insight into the evolutionary development of orchid flowers and fruits, the orchid species Erycina pusilla was studied. The evolutionary origin of the median petaloid sepal, the callus on the labellum, and the stelidia was studied.

Developing robust algorithms and theory for establishing cause-effect relationships from observational data that scale up to large data sets

Indicators to measure progress in de-linking economic growth and environmental pressure.

Promotor: J.M. van den Broek Co-promotor: M.C. de Vries

The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.

Large carnivores and humans, along with their livestock, have co-existed for thousands of years. However, human population growth and an increase in economic activities are modifying the landscape for large carnivores and their prey.

Traditionally, vaccines are administered intramuscularly using conventional hypodermic needles, which cause pain and distress. Microneedles are very short needles (smaller than 1 mm) that are practically invisible to the naked eye.

Breeding for resistance becomes more and more important because we want to reduce the use of pesticides. A fast and cheap alternative can be to make use of morphological or chemical markers.

Exploring linkages between energy and material use and implications for sustainable development.

Mechanical metamaterials are man-made materials which derive their unusual properties from their structure rather than their composition.

A management strategy has been developed for field margins to reduce pesticide drift to non-target areas and to promote biodiversity on arable land. To this end, 3 and 6 m wide strips along the edges of winter wheat, sugar beet and potato crops have been left unsprayed with herbicides and insecticides…

The major and ultimate aim of metabolomics is to obtain an answer to a specific biological or clinical question.

Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.

One of the key quests in astronomy is to study the growth and evolution of galaxies across cosmic time. Radio observations provide a powerful means of studying the formation of stars and subsequent buildup of distant galaxies, in a way that is unbiased by the presence of dust.

Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M.R.V. Chaudron, Co-Promotor: M.T.M. Emmerich

Promotor: Prof.dr. E. Bouwman, Co-Promotor: S. Bonnet

Plants produce an astonishing variety of secondary metabolites (SMs) which are thought to play vital roles in the fitness of plants through ecological interactions.

In this thesis,

Promotor: M. Franx, Co-Promotor: I.F. Labbé

Promotores: H.W. Lenstra, K. Belabas (University of Bordeaux)

Lecture

In het raamwerk van de nationale clusters in de wiskunde heeft NWO zeven voorstellen voor een tenure track positie goedgekeurd. Een van deze voorstellen is: 'Moduli, metrics, models, and arithmetic of Shimura varieties' door Bas Edixhoven van het Leidse Mathematische Instituut.

Het onderzoekscluster Geometry and Quantum Theory (GQT) heeft aan Björn de Rijk, in augustus 2012 afgestudeerd bij Marcel de Jeu en huidig MI promovendus, de GQT Student Prize 2011-2012 toegekend voor zijn masterscriptie “The Order Bicommutant”.

Governance and Global Affairs

Humanities, Institute for Area Studies

Science, Leiden Institute of Physics (LION)

Humanities, Institute for Area Studies, Korean Studies

Science, Leiden Institute of Advanced Computer Science (LIACS)

Science, Institute of Environmental Sciences (CML)

Humanities, Institute for Area Studies

Humanities, Institute for Area Studies

Humanities, Institute for Area Studies

Science, Institute of Environmental Sciences (CML)

Science, Institute of Environmental Sciences (CML)

Science, Institute of Environmental Sciences (CML)