Science, Institute of Biology Leiden (IBL)

Science, Leiden Academic Centre for Drug Research (LACDR)

In this research group, led by Dr. Joost Beltman, the aim is to employ mathematical and computational dynamical modelling approaches in order to quantitatively and mechanistically understand the dynamical behaviour and regulation of intracellular networks of genes, proteins and metabolites as well as…

Science, Institute of Biology Leiden (IBL)

Science, Leiden Academic Centre for Drug Research (LACDR)

Vaccines are an extraordinary category of biopharmaceuticals. They are usually prophylactic and come in many types, from whole bacteria to peptides and nucleic acids. They are very cost effective and almost every human on the planet is vaccinated. The latter mandates that vaccines have to be extremely…

Methods of treatment for chronic illnesses are limited. Doctors and researchers at Leiden University Medical Center (LUMC) and Leiden University are working on new therapies as an alternative for organ transplants. The goal is to cure the illnesses by restoring organs to their original function. Stem…

Terrorism experts Daan Weggemans (Leiden University) and Beatrice de Graaf (Utrecht University) conducted one of the first scientific studies on the societal reintegration of jihadist former detainees. They showed that the reintegration process isn't without problems. Their conlusions are presented…

The Chemical Probe Facility is part of the Leiden Early Drug Discovery & Development (LED3) center. Activity-based protein profiling (ABPP) is one of the pillars of chemical biology. ABPP determines the activity of entire protein families in living cells and tissues under physiological conditions, such…

The research of the Van Eck Group focusses on 3 interconnected research lines: 1) Identification and therapeutic targeting of key pathways/regulators in macrophages essential for prevention of atherosclerotic lesion development or stimulation of regression of existing lesions, 2) Atherosclerosis as…

The need for novel drugs as well as innovations in their development and application is as urgent as ever. Below we present our vision , mission, and our key research areas.

Leiden has one of the most petrified inner-cities of The Netherlands. This is not beneficial for the biodiversity crisis and Leiden University, with a significant number of buildings within the Singels, should be more proactive on this matter. Currently, LUGO is taking steps with internal departments…

The BioMedical Metabolomics Facility Leiden (BMFL) offers a highly structured environment for advanced metabolomics studies. BMFL builds on fully validated, state-of-the-art platforms that each cover a part of the human metabolism and together span the complete human metabolome.

MA student African Studies Eline Sleurink is currently on an internship in Accra, the capital of Ghana. She’s sharing her adventures on The Leidener, a blog that is run by international students of Leiden University.

Under the urgency of the Corona pandemic, and driven by both national and international projects dedicated to the creation of FAIR COVID data, the GO FAIR Foundation has worked with its stakeholder community to consolidate a broad range of technologies into the Three-Point FAIRification Framework (3PFF).…

Protein chains typically fold to function. Folding is a complex process and if done correctly leads to a unique functional fold topology for a given protein chain. Other topologies are also possible but are often non-functional or toxic. These misfolded proteins are then unfolded and subsequently refolded…

Toxys, Leiden University and Leiden University Medical Center have agreed immediately to commercialise and also develop further the ToxProfiler technology invented at the two institutions. ToxProfiler allows for rapid toxicity hazard identification of novel and existing drugs, chemicals, and other substances.…

IBL-researcher Phil Elks in the group of Annemarie Meijer won the Cell Observatory Publication of the Year 2013. He received the award for his paper in PLoS Pathogens, showing that activation of hypoxia signaling protects against mycobacterial infection.

In a recent publication in Nature Sustainability, an international team led by Josephine Chambers from Wageningen University, and including Marja Spierenburg from the Institute of Cultural Anthropology and Development Sociology at Leiden University, have developed a practical tool for researchers and…

Young transgender people are able to decide together with their parents on a reversible intervention with puberty blockers. These are the results of a study by LUMC Curium and Amsterdam UMC of 74 young people undergoing treatment. Ninety percent of the young people studied proved able to make an informed…

In a publication in Science, Noam Zelcer from the Division of Biopharmaceutics describes a previously unrecognized pathway to regulate LDL-cholesterol levels. He is also able to modulate this pathway. This opens the possibility for complementing and improving the efficacy of statins: A class of drugs…

Stephanie Rap and Yannick van den Brink, both assistant professor at the Department of Child Law, presented their research at the 11th EU Forum on the rights of the child: Children deprived of their liberty and alternatives to detention, which took place in Brussels from 6 to 8 November 2017.

Gender beliefs father make bigger difference

Chemist Liubov Belyaeva, psychologist Janna Marie Bas-Hoogendam and LUMC researcher Elisa Giacomelli have received a Rubicon Grand and will therefore be able to conduct research at a top institution abroad.

What and how are we measuring in research of learner-learner interaction? Irena Galikyan (PhD candidate at ICLON) defends her dissertation on this subject on 14 April.

She has held office for over a hundred days, and is enthusiastic about what she has seen of the University thus far. Bursting with energy, she has plans aplenty for the teaching. An interview with ‘new’ Vice-Rector Magnificus of Leiden University, Hester Bijl.

Lecture

If mankind wants to survive into the 22nd century, we will need to change the way we live drastically. The human impact on our planet is everywhere, we are changing the atmosphere, the oceans and the land, leading to global warming, climate change, loss of biodiversity and pervasive pollution. There…

Alexander Kros studies supramolecular systems in a biological environment. The unifying theme between the projects in my lab is specific molecular recognition, i.e. the intermolecular interaction between complementary molecules with high affinity and selectivity. Studying, imitating and dissecting processes…

Science, Institute of Environmental Sciences (CML)

Current research at the Skin Barrier and Vaccination group.

Science, Leiden Academic Centre for Drug Research (LACDR)

On Friday October 25th the fourth annual Jan Reedijk Symposium will be held. The main lectures of the day will be

Besides the project Conference and Winter School, the Food Citizens? research has profiled in numerous societal and interdisciplinary venues, online and offline, over the last year. Here is a brief summary with linked online resources.

The course Designing Your Life helps students navigate their career pathways. As it turns out, these pathways are full of twists and turns and - as with many journeys - you only make progress once you gather the courage to take the first step.

Global science research serves the needs of the Global North, and is driven by the values and interests of a small number of companies, governments and funding bodies, finds a major new international study published today. As such, the authors find, science, technology and innovation research is not…

An astonishing twelve students from Leiden University have received a Young Talent Award from the Royal Holland Society of Sciences and Humanities in Haarlem, a record. During the festive ceremony on 25 November, five master students received a Young Talent Graduation Award for their thesis and seven…

The challenge: Building a tool to detect chemical compounds that individually cause non-lethal stress to bacteria, but that are lethal in combination. A team of thirteen Leiden students are taking up this challenge in the annual ‘international Genetically Engineered Machine’ (iGEM) competition for applications…

Salma Balazadeh, Víctor Carrión, and Jos Raaijmakers, biologists at the Institute of Biology Leiden (IBL), have successfully applied for an NWO grant and got awarded 730.000 euros. The board of NWO Domain Applied and Engineering Sciences awarded funding for their project within the Open Technology Programme…

On September 9th 2009, the study Life Science and Technology (LS&T) celebrates its 10th anniversary. In 1999, a group of enthusiastic pioneers within the Technical University Delft (TUD) and Leiden University (LU) founded a novel study based on the biotechnological expertise of research institutes within…

Image from ESOF Forum programme page.

Using musical cues to learn a physical task significantly develops an important part of the brain, according to a new study co-authored by Leiden psychologist Rebecca Schaefer. The results are published in the journal Brain & Cognition.

Man-made sounds in and around the oceans stress marine life and have an impact on marine species and ecosystems by changing the underwater acoustic climate. Hans Slabbekoorn from the Institute of Biology Leiden pleads for technical solutions to mitigate problems of noise pollution. Science review paper…

We use zebrafish as a model organism to study human development and disease as well as animal welfare and environmental impact.

We are pleased to welcome three new colleagues at the Institute of Security and Global Affairs this month: Andrea Bartolucci, Joana Cook and Silvia D'Amato.

He presented his PhD research entitled “Kick-starting drug development; translational systems pharmacology using innovative zebrafish experiments and advanced computational modelling”. During his presentation, Rob highlighted the advancements he made in using zebrafish as model in system pharmacolog…

The international regime governing displacement shows a number of gaps, most notably with regard to (internally) displaced people who are not covered by the definition of refugee of the Refugee Convention. These protection gaps translate into solution gaps for displaced people.

Vicencio Oostra, who defended his PhD-thesis at the IBL successfully in June 2013, published new insights into the hormonal regulation of butterfly responses to fluctuating environments.

Lecture