Centre for Computational Life Sciences (CCLS)
CCLS Past Events 2019
These are CCLS events that have already taken place. PDFs of the presentations will be added once they have been received.
Meeting 23 April 2019
Programme
Ahmed Mahfouz
Untangling Single Cell Data; Interaction, Identification and Intergration
Jelle Goeman
Double Dipping Done Right; Interactive, Statistical Inference in Neuroimaging
Patrick Echtenbruck
Innovage
Drinks & Nibbles at Foobar
Interaction Meeting 24 May 2019
Programme
Break out in Groups and Logo Design
Pitches by Groups and Discussion
Drinks & Nibbles at Foobar
Meeting 18 June 2019, Snellius
Programme
Vivi Rottschäfer
Towards a 3D distribution Model of Drugs in the Brain
Sander Hill
Computational Issues in Mathematical (Plant) Biology
Drinks & Nibbles at Foobar
Meeting 24 October 2019 LUMC, Building 1, J-01-117, Conference Room
Programme
15.00 - 15.10 Welcome with coffee/tea
15.10 - 15.30 Coen van Hasselt - Quantitative modeling in translational and clinical pharmacology (LACDR)
15.30 -15.50 Sirin Yunucu - Translational systems pharmacology modeling for immune-oncology (LACDR)
15.50 - 16.30 Discussion
16.30 - 17.30 Drinks and Nibbles in LAB 071
Meeting 5 November 2019, Gorlaeus, GM 4.13
Speaker
Charles Hoyt, Fraunhofer Institute for Algorithms and Scientific Computing in Sankt Augustin, Germany:
Applications of Biomedical Knowledge Graphs in Drug Discovery
See also: Applications of Knowledge Graphs in Drug Discovery
Abstract:
Drug discovery campaigns are often successful because of a coherence between the identification of key proteins in a disease and their subsequent targeting for modulation. Network representation learning will be presented as a schema-free framework for integrating and jointly modeling several biological relationships from heterogeneous data types like chemical activities, chemical similarity, drugs’ side effects, drugs’ indications, and disease-associated proteins. It will be shown how link prediction tasks in an integrative network are isomorphic to several key tasks in drug discovery such as proteochemometrics, target prioritization, side effect prediction, and drug repositioning. Finally, it will be shown how the underlying network can be directly used to identify and rank potential mechanisms of action for drug repositioning candidates.
19 November 2019 Meeting - Science Club and Bar, Gorlaeus
Programme
16.00 - 16.10 Welcome with Coffee and Tea
16.10 - 16.35 Willem Jespers - Molecular Dynamics and Free Energy Calculation Approaches: What can it do for you
16.35 - 17.05 Alexander Gultyeav - Structural Bioinformatics of Virus RNA's
17.05 - 17.15 Michael Emmerich - NWO Klein Proposal
17.15 - 17.30 Discussion and Announcements
17.30 Drinks and Nibbles at the Science Bar
29 November 2019 Meeting - Hortus Botanicus
Lunch at the Faculty Club
Julia Handl, Manchester University - Data-driven Optimization: Using machine learning principles to focus the search in evolutionary optimization
Workshop in the Hortus Botanics: Herbs and Spices or Tour of the Botanical Gardens
Lindsey Burggraaff LACDR - Challenges in Computational Drug Discovery - Bridging Computer Science and Medicianal Chemistry
Irene Martorelli LIACS - Integration and Computational Analysis of Fungal Metabarcoding Data
Rob van Wijk IBL - The Zebrafish as Whole Vertebrate Organism for Systems Modelling
Thomas Bakkum LIC - Data Processing and Analysis in Correlative Light and Electron Microscopy
Drinks and Nibbles in Het Pakhuis, Doelensteeg 8
