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Centre for Computational Life Sciences (CCLS)

CCLS Meetings in 2020

Webinars: We are organising virtual events only until further notice; please return to this website for updates.

Online events only until further notice

All upcoming reali-life events have been cancelled until 1st September 2020, due to the restriction implemented by the Dutch governement as a consequence of to the Corona virus.
 

Meeting Schedule

21 January 2020 Erik van den Akker & Boudewijn Lelieveldt @ LUMC

18 February 2020 CANCELLED

 19 March 2020 CANCELLED 

Webinars

23 April 2020 at 2 pm - Lu Cao - High Throughput Image Analysis for Cardiomyocyte - Kaltura Live Room

26 May 2020 - 2 pm Webinar - Barbara Scalvini (LACDR) - 'Circuit topology of biopolymers: from theory to applications to real biological chains - Kaltura Live Room: 
https://smart.newrow.com/#/room/xqz-283

 16 June 2020 - 4 pm- Webinar - Oliver Kramer, Oldenburg University, Germany Titled "Evolutionary Multi-Objective Design of SARS-CoV-2 Protease Inhibitor Candidates"  on Kaltura: https://smart.newrow.com/#/room/xqz-283

14 July @ 4 pm: Pub Quiz in Kahoot: REGISTER your team. Prove your knowledge on trivia, films, music, life sciences, informatics etc.

No meetings in August due to holiday 

Monday 21 September 2020 at 2 pm in Teams -Nigel Greene, PhD, Director, Data Science and Artificial Intelligence, Imaging and Data Analytics, Clinical Pharmacology and Safety Sciences, AstraZeneca

Tuesday 20 October 2020 at 2 pm Agnieszka Wegrzyn 

Post-doc Division of Systems Biomedicine and Pharmacology,
Leiden Academic Centre for Drug Research, Leiden University

Register by emailing: Mischa

Tuesday 17 November 2020 at 2 pm Ariane Briegel, Institute Biology Leiden

Title: Structure and function of the bacterial chemotaxis system in pathogens and microbial communities.

Abstract: Most motile bacteria contain a highly sensitive and adaptable sensory system composed of clusters of chemoreceptors. This chemosensory system is used to detect changes in nutrient concentrations, allows the cells to navigate towards preferential environments and is also involved in host infection by some pathogenic bacteria. While it is one of the best understood signaling systems to date, unraveling structure and function of the bacterial chemotaxis system remains challenging. High-resolution analysis using methods are inherently limited to structural fragments and rely on specimens taken out of their natural environment. Thus, they lack the larger context of the native system. Here, we use cryo-electron tomography (cryoET) to study the three-dimensional architecture of the bacterial chemoreceptor arrays. We identified species-specific characteristics of this system of selected pathogens, such as in Treponema denticola (periodontal disease) and Vibrio cholerae (cholera). However, not all bacteria are motile, but can still benefit from chemotactic behavior: we have gained insight how non-motile bacteria can benefit from chemotactic microbes that share the same environment.

 

Register by emailing: Mischa

No December meeting due to holidays

 

Ideas, thoughts and suggestions on venues, subjects and events are very welcome! Email: Mischa Hautvast

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