Research output

• Evolvability and epistasis studied through the lens of an antibiotic resistance enzyme

  Dissertation

  • Science
    • Leiden Institute of Chemistry (LIC)
    • Fundamental Research in Chemical Biology
    • Macromolecular Biochemistry

  

• Microstructural and Metabolic Alterations in the Zebrafish Brain Induced by Toll-Like Receptor 2 Deficiency

  Dissertation

  • Science
    • Leiden Institute of Chemistry (LIC)
    • Fundamental Research in Chemical Biology
    • Macromolecular Biochemistry

  

• Enzyme-substrate interactions in the processive enzyme xylanase

  Dissertation

  • Science
    • Leiden Institute of Chemistry (LIC)
    • Fundamental Research in Chemical Biology
    • Bio-organic Synthesis
    • Macromolecular Biochemistry

  

• Thermostable Nanodiscs for the development of novel biopharmaceuticals

  Dissertation

  • Science
    • Leiden Institute of Chemistry (LIC)
    • Fundamental Research in Chemical Biology
    • Macromolecular Biochemistry

  

• Design and synthesis of metal-based chemotherapeutic agents for targeted DNA interactions or DNA repair pathway modulation

  Dissertation

  • Science
    • Leiden Institute of Chemistry (LIC)
    • Fundamental Research in Chemical Biology
    • Macromolecular Biochemistry
    • Metals in Catalysis, Biomimetics & Inorganic Materials
    • Dame Lab / Chromatin Organization & Dynamics

  

• Substrate adaptability of β-lactamase

  Dissertation

  • Science
    • Leiden Institute of Chemistry (LIC)
    • Fundamental Research in Chemical Biology
    • Macromolecular Biochemistry

  

• The dynamic organization of prokaryotic genomes: DNA bridging and wrapping proteins across the tree of life

  Dissertation

  • Science
    • Leiden Institute of Chemistry (LIC)
    • Fundamental Research in Chemical Biology
    • Macromolecular Biochemistry
    • Dame Lab / Chromatin Organization & Dynamics

  

• Evolutionary adaptability of β-lactamase: a study of inhibitor susceptibility in various model systems

  Dissertation

  • Science
    • Leiden Institute of Chemistry (LIC)
    • Fundamental Research in Chemical Biology
    • Macromolecular Biochemistry

  

• Identification and characterization of viral Xrn1-resistant RNAs

  Dissertation

  • Science
    • Leiden Institute of Chemistry (LIC)
    • Fundamental Research in Chemical Biology
    • Macromolecular Biochemistry
    • Dame Lab / Chromatin Organization & Dynamics

  

• Essentiality of conserved amino acid residues in β-lactamase

  Dissertation

  • Science
    • Leiden Institute of Chemistry (LIC)
    • Fundamental Research in Chemical Biology
    • Macromolecular Biochemistry

  

• The relation between dynamics and activity of phospholipase A/acyltransferase homologs

  Dissertation

  • Science
    • Leiden Institute of Chemistry (LIC)
    • Fundamental Research in Chemical Biology
    • Macromolecular Biochemistry
    • Molecular Physiology

  

• The environmentally-regulated interplay between local three- dimensional chromatin architecture and gene expression

  Dissertation

  • Science
    • Leiden Institute of Chemistry (LIC)
    • Fundamental Research in Chemical Biology
    • Macromolecular Biochemistry
    • Dame Lab / Chromatin Organization & Dynamics

  

• Deciphering the complex paramagnetic NMR spectra of small laccase

  Dissertation

  • Science
    • Leiden Institute of Chemistry (LIC)
    • Fundamental Research in Chemical Biology
    • Biophysical Organic Chemistry
    • Macromolecular Biochemistry

  

• Understanding protein complex formation: The role of charge distribution in the encounter complex

  Dissertation

  • Science
    • Leiden Institute of Chemistry (LIC)
    • Fundamental Research in Chemical Biology
    • Macromolecular Biochemistry

  

• Dynamic organization of bacterial chromatin by DNA bridging proteins

  Dissertation

  • Science
    • Leiden Institute of Chemistry (LIC)
    • Fundamental Research in Chemical Biology
    • Macromolecular Biochemistry
    • Dame Lab / Chromatin Organization & Dynamics