News
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New treatments for life-threatening disease sepsis 12 July 2023
Due to the increasing resistance to certain antibiotics, the life-threatening condition sepsis is becoming harder to treat. For her PhD project, Leide...
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Grant Elise Mathilde Fund & LUF: Using virus to kill bacteria: design of innovative phage-antibiotic combination treatments to combat antimicrobial resistance 05 July 2023
Phage therapy is a novel yet unmatured therapeutic approach in the face of the crisis of antimicrobial resistance (AMR). Dr. Tingjie Guo received a gr...
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Improving painkiller dosing in the clinic 25 November 2022
Children, cardiac surgery patients or people who are obese. How can we improve the dosing of painkillers for these patients? Hospital pharmacist Sjoer...
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Children become bacteria to learn about antibiotics 21 November 2022
Last Friday the global Antibiotics Awareness Week begun: an entire week dedicated to antibiotic use. Antibiotics researchers from the LACDR therefore ...
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Developing new therapies to fight muscle disease 26 September 2022
Biophysicist Alireza Mashaghi and his collaborators are taking up the fight against muscular dystrophy: genetic disorders that cause muscle weakness. ...
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Researchers tackle antibiotic-resistant bacteria 06 May 2022
When a bacterium becomes more resistant to one antibiotic, it sometimes becomes more sensitive to another. To better understand this interaction, rese...
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Combating antibiotic resistance together 24 March 2022
Antibiotic resistance is a common problem among patients. The European Project TIPAT trains pharmacologists, microbiologists and immunologists of six ...
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Leiden researchers join forces against tuberculosis 24 March 2022
About one and a half million people worldwide die each year from tuberculosis. For thirty years, therapy with antibiotics has been the same, while it ...
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Drugging the undruggable: NWO Open Competition grant for Alireza Mashaghi 04 January 2022
Finding structure in disordered proteins and developing drugs for undruggable diseases: it might sound like mission impossible, but pharmacologist Ali...
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Bioprinting human tissues for drug testing 05 October 2021
Bioprinters that enable scientists to engineer complex tissues and organs. It sounds like science-fiction, but not for the scientists of the Alireza M...
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Combatting antibiotic resistance in a clever way 28 September 2021
When you become very good at one thing, that sometimes comes at the expense of something else. Such trade-offs also apply to bacteria. When becoming m...
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Improving the treatment of newborn babies with life-threatening sepsis 12 August 2021
Coen van Hasselt’s pharmacology group collaborated on a study recently published in the renowned Lancet Infectious Diseases. The international team ma...
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How do children's kidneys eliminate drugs? 09 August 2021
What dose of medicine do you give a child? That depends to a large extent on how quickly their kidneys remove the drug from the blood. For ethical rea...
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Master projects continue thanks to lab automation 09 August 2021
The fact that corona has created a wave of creativity is evident when walking around in the lab of pharmacologist Coen van Hasselt from the LACDR. Sud...
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Virtual children help prevent withdrawal syndrome in real children 25 May 2021
When children wean off from heavy medication, they often experience withdrawal symptoms. The severity of these symptoms is often difficult to predict....