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Top Lectures: Dolf Weijers

Thursday 12 March 2020
Top Lectures 2020
Sylviusweg 72
2333 BE Leiden

Be welcome at the Top Lectures from the Institute Biology Leiden! Twice a month researchers at the IBL invite (inter)national speakers to give a masterclass to students and hold a public accessible lecture for a general audience. Afterwards, there is opportunity for a drink. Access is free of charge!

The programme is as follows:

  • 15.00 - Masterclass for students
  • 16.00 - Public lecture for general audience and students
  • 17.00 - Drinks for all
  • 18.00 - End

Your host for this edition will be Professort of Plant Developmental Genetics Remko Offringa. He invited Dolf Weijers, Chair of Biochemistry at the WUR. Prof. Dr. Dolf Weijers will talk about convergence of cell polarity systems across multicellular kingdoms.

Short summary: Cells in multicellular organisms organise along body and tissue axes. Cellular processes, such as division plane orientation, must be aligned with these polarity axes to generate functional 3-dimensional morphology, particularly in plants, where cell walls prevent cell migration. While some polarly localized plant proteins are known, molecular mechanisms of polarity establishment or its translation to division orientation are elusive, in part because regulators in animals and fungi appear to be missing from plant genomes. Cell polarity is first established in the embryo, but this has long been an intractable experimental model. In the past years, genetic and imaging tools have been developed that allow using the early Arabidopsis embryo as a model for understanding the mechanisms that drive cell polarity and oriented cell divisions. In this seminar, I will present our recent work, focusing on the identification of a novel, deeply conserved polarity system.

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