Universiteit Leiden

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This Week's Discoveries | 3 December 2019

Tuesday 3 December 2019
Niels Bohrweg 2
2333 CA Leiden
De Sitterzaal

First lecture

Euclid: exploring the dark Universe

Henk Hoekstra ((Leiden Observatory)
Henk is a Professor of Observational Cosmology at Leiden Observatory. His main area of research is observational cosmology, with a particular focus on the study of dark matter and dark energy using weak gravitational lensing. Since 2011 he is a cosmology coordinator for Euclid, the ESA mission to study the nature of dark energy and many other aspects of our current cosmological paradigm.

In the past century, we have learned much about the origin and evolution of the Universe. We now know the Universe is 13.8 billion years old, but its main ingredients remain a mystery: atoms make up only 5%. The rest consists of dark matter and dark energy, components for which we lack a fundamental physical theory. Better observations are needed to guide theory and ESA’s Euclid satellite is designed to do just that. Euclid is scheduled for launch in 2022 and will map the distribution of dark matter in the Universe as a function of cosmic time.  In this talk, I will present an overview of this exciting project that will test key aspects of the current cosmological paradigm

Second lecture

How to improve morphine dosing in young children?

Bas Goulooze (LACDR)
Bas is a PhD student in the group of Catherijne Knibbe at LACDR. His PhD project involves the use of mathematical models to predict the effect of sedatives and analgesics in patients, with the ultimate aim of improving the dosing of these drugs in the individual patient.

It is common practice to give morphine to children after surgery. However, there is still limited evidence on which morphine doses provide adequate analgesia. Morphine treatment is even more complicated in children younger than three years, as these children cannot communicate their level of pain directly. Therefore, in this work, we modeled the effect of morphine on pain-associated behavioral signs in children after surgery, to gain a better understanding of the pharmacology of morphine and improve dosing in these children.

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