Lecture
Joan van der Waals colloquium
- Date
- Friday 20 September 2019
- Time
- Explanation
- Drinks afterwards.
- Location
-
Oort
Niels Bohrweg 2
2333 CA Leiden - Room
- De Sitterzaal
" Plasmonic Nanoparticles as sensor for single molecules"
We utilize plasmonic gold nanoparticles to detect single unlabeled proteins with high temporal resolution (ms to µs). This allows for monitoring the dynamic evolution of DNA hybridization or protein binding. The technique resolves equilibrium coverage fluctuations, opening a window into Brownian dynamics of unlabeled macromolecules. I will show applications to protein dynamics, protein adsorption processes, and kinetics as well as non-equilibrium soft matter dynamics.