This Week's Discoveries | 18 June 2019
- Tuesday 18 June 2019
- This Week's Discoveries
Niels Bohrweg 2
2333 CA Leiden
- De Sitterzaal
Tuesday 18 June was the last This Week's Discoveries of this academic year. Will we continue the lecture series after the summer holidays. The first This Week's of the new academic year is expected to be on September 24th.
Unravelling stress response networks in plants: from gene regulatory grids to proteome control circuits.
Salma Balazadeh (IBL)
Salma is a Group Leader of the cooperative research group 'Stress Control Networks' at the Max Planck Institute (MPI) of Molecular Plant Physiology in Germany and Associate Professor at the IBL Plant Sciences & Natural Products cluster in Leiden. Her group at the MPI focuses on understanding the signalling mechanisms that trigger responses to environmental stress and unravelling the cellular processes through which plants counteract stress, with the aim to control plant tolerance to secure global food supply.
Theoretical estimation of the plausibility of auxin transport through PIN-containing secretory vesicles
Sander Hille MI)
Sander is an assistant professor in mathematics. In research and education, he has a particular interest in the development and application of mathematical techniques to problems in the Life Sciences, Biology in particular. Concerning his interdisciplinary research in biomathematics, he focusses on population dynamics and the modelling and analysis of signalling networks and transport processes. In fundamental mathematics, his interests are in the topic of deterministic dynamical systems in and stochastic perturbations thereof by means of random interventions at discrete times.
Auxin is a plant hormone that plays an important role in various developmental processes. It is subject to intercellular polar transport. PIN-formed (PIN) auxin efflux carriers are thought to be important in this directional transport. Within the cell, these PIN proteins are transported from the endosome to cell membrane in secretory vesicles. Some researchers have argued that these vesicles will contain auxin and thus contribute to polar auxin transport (PAT). We discuss how, by means of appropriate mathematical modelling in combination with additional dedicated experiments, we estimated the contribution of these vesicles to overall PAT, leading to a conclusion on the plausibility of auxin transport through these secretory vesicles.