FRESH Lecture: (Photo)-catalysts based on surface functionalized laccases
- Dr. Thierry Tron (Aix Marseille Université)
- Thursday 31 January 2019
- Gorlaeus Building
2333 CC Leiden
Laccases are well known biocatalysts with great robustness, high oxidation power and substrate versatility. Their unique set of copper centres - a near-surface located mononuclear type 1 and an embedded tri-nuclear cluster (TNC) made of a type 2 and a binuclear type 3 - couple the oxidation of substrates (organic or metal ions) to dioxygen reduction. We shape new catalysts based on oriented functionalizations of a laccase surface with different “plug-ins”.
From our initial demonstrations on bi-molecular systems - a sensitizer/laccase system coupling the light driven four-electron reduction of dioxygen to water to the photo-oxidation of styrene or a Pd(II)/ laccase system competent for the aerobic oxidation of alcohol in mild conditions - we will present our latest architectures based on the oriented grafting of the enzyme surface.[6 ,7]
Prospects on olefin oxidation catalysts and laccase functionalized electrode materials will be discussed.
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