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Dual function of primary somatosensory cortex in what marks individual differences in cognitive flexibility: a resting state fMRI study using multiband EPI

9 November 2018
LACG meetings
Lipsius Building
Cleveringaplaats 1
2311 BD Leiden


Resting-state functional connectivity can be leveraged to investigate individual differences in executive functions, in particular by employing multiband EPI technique in which functional integration among brain regions is better characterized. To this end, a within network functional connectivity analysis was done on resting-state data acquired via multiband EPI (multiband factor = 4, TR = 690ms) to investigate both network shape and amplitude in three resting statenetworks (RSNs) of interest namely: 1) frontoparietal; 2) salience; and 3) default mode networks, between two groups of participants with regard to their performance in language task switching. Results demonstrated that frontoparietal network shape is different between these two groups of participants due to increased coupling of left primary somatosensory cortex with dorsolateral prefrontal cortex (dlPFC) in group with smaller switch costs and increased coupling of right primary somatosensory cortex with inferior parietal cortex (IPC) in group with larger switch costs in language task switching. Network amplitude in these three RSNs did not show any between group differences. As switch cost is considered a reliable indicator of cognitive flexibility, with respect to the results of this study, we claim that primary somatosensory cortex has a dual function in coupling with dlPFC and IPC in frontoparietal network, causing between group differences in the shape of this network, and in fact in what characterizes individual differences in cognitive flexibility.

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