|Series||This Week's Discoveries|
Niels Bohrweg 2
2333 CA Leiden
In the hands of the chaperones: how do proteins find their shapes?
Alireza Mashaghi (LACDR) is assistant professor and PI of the Laboratory for Systems Biophysics and Precision Medicine in the Analytical Bioscience Division of LACDR. His group develops and uses theoretical and experimental approaches to address both basic and applied problems. Fundamental research is focused on the single-molecule analysis of biomolecular structure and dynamics. In particular, how chaperones assist conformational search of biomolecules and how molecular topology defines function, dynamics and evolution of biomolecules. Other areas of interest are systems biophysics and complex networks. Applied research is focused on medical diagnostics, nanomedicine and label free detection of biomolecular systems for medical applications (in partnership with the group of Thomas Hankemeier). His paper 'Alternative modes of client binding enable functional plasticity of Hsp70' was published in Nature last November.
Jargon in hydrology
Ionica Smeets (IBL) is professor of science communication and leader of the group Science, communication and society. One of her research interests is the different definitions laymen and experts have of jargon and the misunderstandings that arise from this. She will discuss known problems and a current study in the field of hydrology.