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Looking back at the LACDR Fall Symposium: The 4 dimensions; in space and time

Tuesday 22 November 2016
Leiden University, Gorlaeus Laboratories, Lecture Hall C1 Free entrance after registration
Gorlaeus Building
Einsteinweg 55
2333 CC Leiden

In a living system, events occur in space and time, within the spatial boundary of that system. Therefore, in order to understand the system, information is needed on space- and time- dependency of components that contribute to the events. By examining the linkages and interactions between these components, systems science is an important approach to fully understand living systems.

These four dimensions, space and time, were at the centre of the programme of the recent LACDR Fall Symposium. Host of the symposium was Dr. Liesbeth de Lange, who led us through the several presentations.

Imaging and Internal clocks

Considering the dimension of space, Prof. Andreas Linninger (University of Illinois, Chicago, USA) introduced us to us the use of 3D brain images for the development of a 3D brain vascular system model. This was followed by Prof. Joke Meijer of the LUMC, who presented the biological clock, showing the impact of time on the living system, including how this may affect drug concentrations and effects.

Suzanne Hovinga Award 2016

A special place in the programming was provided to the presentation of the Suzanne Hovinga Award. Dr Laura Heitman explained this special award, named in remembrance of late Suzanne Hovinga, a very inspiring student of Bio-pharmaceutical sciences,- and which prize encourages Bio-Pharmaceutical Students in the excellent quality of their work, and to continue to excel.

This year the Suzanne Hovinga Award was awarded to Maarten Swart who graduated for his final thesis "Irf5 and atherosclerotic plaque "vulnerability" with both the maximum grades of a 10, for his theoretical work, as for his practical work. A remarkable achievement! From Oxford, through Skype, he presented us the short version of his work about these "vulnerable plaques".

Ageing and 3D stacking

In the second part of the symposium, Dr. Anton Roks from Erasmus MC led us through a more in-depth analysis of the factors in time that determine our ageing process, at the blood vessel level and Prof. Joke Bouwstra of our Cluster BioTherapeutics presented the importance of 3D stacking of densely packed lipid layers in the skin, and how this 3D structure can make all the difference between a healthy skin or a skin disease such as atopic dermatitis.

In all, the Symposium was a great success!


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